aldh3a2
Share
  • Official Full Name
  • aldehyde dehydrogenase 3 family, member A2
  • Background
  • Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • ALDH3A2; aldehyde dehydrogenase 3 family, member A2; ALDH10, SLS; fatty aldehyde dehydrogenase; FALDH; aldehyde dehydrogenase 10; microsomal aldehyde dehydrogenase; aldehyde dehydrogenase family 3 member A2; SLS; ALDH10; FLJ20851; DKFZp686E23276
Cat.#:ALDH3A2-446HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALDH3A2 Protein, GST-tagged
+Inquiry
Cat.#:ALDH3A2-493HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Aldehyde Dehydrogenase 3 Family, Member A2, His-tagged
+Inquiry
Cat.#:ALDH3A2-494HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Aldehyde Dehydrogenase 3 Family, Member A2, GST-tagged
+Inquiry
Cat.#:ALDH3A2-9558HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ALDH3A2, His-tagged
+Inquiry
Cat.#:ALDH3A2-1527MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ALDH3A2 Protein
+Inquiry
Cat.#:ALDH3A2-293CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ALDH3A2 Protein, His-tagged
+Inquiry
Cat.#:ALDH3A2-1371CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ALDH3A2
+Inquiry
Cat.#:ALDH3A2-8917HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ALDH3A2 293 Cell Lysate
+Inquiry

Involved Pathway

ALDH3A2 involved in several pathways and played different roles in them. We selected most pathways ALDH3A2 participated on our site, such as Glycolysis / Gluconeogenesis, Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH3A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycolysis / Gluconeogenesis
GPI; HKDC1; GM5506; PFKM; ENO2; ALDH9A1B; PGAM1B; ALDOA; PKLR; LDHBA
Pentose and glucuronate interconversions
UGT1A7; AKR1B1L; SORD; UGT1A9; AKR1B8; UGT1A6A; AKR1A1A; ALDH2; ALDH2.1; UGT2B7
Ascorbate and aldarate metabolism
UGT1A6; ALDH9A1B; UGT1A7; ALDH2; UGT2B7; UGT2A2; UGT5G1; UGT1A4; ALDH9A1A.1; UGT2A3
Fatty acid degradation
ADH1; CPT1B; ECI1; ACADM; ACSL5; ACSL3; ACOX3; ACAT1; ADH5; ACAT2
Valine, leucine and isoleucine degradation
HADHB; ALDH3A2A; ACADM; BCAT1; BCKDHB; HADH; AOX2P; AOX3; ALDH6A1; OXCT1A
Lysine degradation
TMLHE; OGDHL; WBP7; SUV420H2; GCDHA; AGPHD1; PLOD2; OGDHA; ALDH7A1; SETD1BA
Arginine and proline metabolism
SAT1; DAO; SRM; AZIN2; ALDH2.2; CKM; NOS2B; SMOX; CKB; DAO.1
Histidine metabolism
ALDH1A3; CARNS1; MAOA; CNDP2; CNDP1; ASPA; ALDH2.1; HDC; ALDH2; AOC1
Tryptophan metabolism
CYP4F12; TPH1A; INMT; ALDH3A2; ANI_1_2390104; TDO2; HADHAB; ALDH1B1; ALDH2; AOX3L1
beta-Alanine metabolism
DPYDB; AOC3; ALDH9A1B; ALDH2.2; UPB1; CNDP1; SMS; ALDH3B2; CNDP2; AOC2
Glycerolipid metabolism
ALDH9A1B; AGPAT3; AGPAT2; DGKAA; AGPAT6; MGLL; CEL.1; CELL; ALDH3A2A; GK
Pyruvate metabolism
ME2; HAGHL; FH1; MDH2; MPC1; ALDH9A1A.1; PKM; LDHA; LDHC; ACSS1
Metabolic pathways
ST6GALNAC6; NME2A; CRLS1; TPH1; ODC1; CDS1; AK4; SARDH; PIPOX; GFPT2

Protein Function

ALDH3A2 has several biochemical functions, for example, 3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase [NAD(P)+] activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH3A2 itself. We selected most functions ALDH3A2 had, and list some proteins which have the same functions with ALDH3A2. You can find most of the proteins on our site.
Function
Related Protein
Function 3-chloroallyl aldehyde dehydrogenase activity
Related Protein ALDH2.1; ALDH3A2A; ALDH3A2B; ALDH1A1; ALDH3B2; ALDH3A1; ALDH3B1; ALDH3A2; Aldh1a7; ALDH9A1
Function aldehyde dehydrogenase (NAD) activity
Related Protein ALDH3A2; ALDH9A1; ALDH16A1; ALDH1B1; ALDH7A1; ALDH9A1A.1; ALDH3A2B; ALDH1A1; ALDH6A1; ALDH3B2
Function aldehyde dehydrogenase [NAD(P)+] activity
Related Protein ALDH3A1; ALDH3A2; ALDH1A3; ALDH3B2; ALDH3B1; ALDH2; ALDH3A2A; ALDH3A2B
Function long-chain-alcohol oxidase activity
Related Protein ALDH3A2
Function long-chain-aldehyde dehydrogenase activity
Related Protein ALDH3A2
Function medium-chain-aldehyde dehydrogenase activity
Related Protein ALDH3A2

Interacting Protein

ALDH3A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDH3A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDH3A2.
Stag2; USP50; Mad2l2; p29991-pro_0000037946; midostaurin; AIM2; PPP6R2; GABARAP; 1C; MME; CAPZA2; GABARAPL2; Tubg1; Smn1; KPNB1; Prkci; Atp7a; ATL3; Tnpo1