| Description : |
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
Mammalian cells |
| Species : |
Human |
| Tag : |
Flag |
| Form : |
25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : |
54.7 kDa |
| AA Sequence : |
MELEVRRVRQAFLSGRSRPLRFRLQ QLEALRRMVQEREKDILTAIAADLC KSEFNVYSQEVITVLGEIDF MLENLPEWVTAKPVKKNVLTMLDEA YIQPQPLGVVLIIGAWNYPFVLTIQ PLIGAIAAGNAVIIKPSELS ENTAKILAKLLPQYLDQDLYIVING GVEETTELLKQRFDHIFYTGNTAVG KIVMEAAAKHLTPVTLELGG KSPCYIDKDCDLDIVCRRITWGKYM NCGQTCIAPDYILCEASLQNQIVWK IKETVKEFYGENIKESPDYE RIINLRHFKRILSLLEGQKIAFGGE TDEATRYIAPTVLTDVDPKTKVMQE EIFGPILPIVPVKNVDEAIN FINEREKPLALYVFSHNHKLIKRMI DETSSGGVTGNDVIMHFTLNSFPFG GVGSSGMGAYHGKHSFDTFS HQRPCLLKSLKREGANKLRYPPNSQ SKVDWGKFFLLKRFNKEKLGLLLLT FLGIVAAVLVKAEYYTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining. |
| Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Storage : |
Store at -80 centigrade. |
| Concentration : |
>50 ug/mL as determined by microplate BCA method. |
| Preparation : |
Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Protein Families : |
Druggable Genome, Transmembrane |
| Protein Pathways : |
Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation |
