|Official Full Name||aldehyde dehydrogenase 6 family, member A1|
|Background||This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.|
|Synonyms||ALDH6A1; aldehyde dehydrogenase 6 family, member A1; MMSDH; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; malonate-semialdehyde dehydrogenase; aldehyde dehydrogenase family 6 member A1; mitochondrial acylating methylmalonate-semial|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ALDH6A1 involved in several pathways and played different roles in them. We selected most pathways ALDH6A1 participated on our site, such as Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Inositol phosphate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH6A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Valine, leucine and isoleucine degradation||HMGCLL1; HIBADH; ALDH9A1B; PCCB; ACAA2; ALDH9A1; HMGCL; HIBCH; DLDH; AOX3L1|
|beta-Alanine metabolism||SRM; AOC2; ALDH2; ALDH6A1; MLYCD; HADHAB; GAD1B; ACADM; CNDP2; GAD1|
|Inositol phosphate metabolism||INPP5E; PLCD1A; NUDT4; SYNJ2; PI4KB; IPMKB; ALDH6A1; INPP4B; MTMR4; PIK3CG|
|Propanoate metabolism||DLDH; ECHDC1; MUT; ACAT1; PCCA; LDHAL6A; MCEE; BCKDHB; SUCLG2; ACACA|
|Metabolic pathways||CYP2C54; CYP2J5; CYP4A10; CERS1; ATP6V0A4; HLCS; NDUFC1; CYP2P7; RIMKLB; PC|
|Carbon metabolism||PKLR; GPIA; HADHAB; IDH3B; GOT1; ACADM; FBP2; PDHA1A; AMT; PSPH|
ALDH6A1 has several biochemical functions, for example, aldehyde dehydrogenase (NAD) activity, fatty-acyl-CoA binding, malonate-semialdehyde dehydrogenase (acetylating) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH6A1 itself. We selected most functions ALDH6A1 had, and list some proteins which have the same functions with ALDH6A1. You can find most of the proteins on our site.
|aldehyde dehydrogenase (NAD) activity||ALDH1A1; ALDH1B1; ALDH1L1; Aldh1a7; ALDH6A1; ALDH9A1A.1; ALDH7A1; ALDH3A2; ALDH9A1; ALDH3A2A|
|fatty-acyl-CoA binding||ACADVL; ACBD5; ALDH6A1; ACADM; GCDHB; SOAT1; ACAD8; ACOX3; ACBD4; ACAD11|
|malonate-semialdehyde dehydrogenase (acetylating) activity||ALDH6A1|
|methylmalonate-semialdehyde dehydrogenase (acylating) activity||ALDH6A1|
|poly(A) RNA binding||NGDN; RPS27A; RPS27.1; PTRH1; UBE2O; PRPF6; DHX8; RPS11; RPL8; DARS|
|thiolester hydrolase activity||ALDH6A1; ACOT5; ACNAT2; UFSP2; PPT2; Acnat1; UFSP1|
ALDH6A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDH6A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDH6A1.
TRMT10C; LMO2; NDUFS7