ALDH6A1 Protein, aldehyde dehydrogenase 6 family, member A1

ALDH6A1

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ALDH6A1

Official Full Name aldehyde dehydrogenase 6 family, member A1
Background This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
Synonyms ALDH6A1; aldehyde dehydrogenase 6 family, member A1; MMSDH; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; malonate-semialdehyde dehydrogenase; aldehyde dehydrogenase family 6 member A1; mitochondrial acylating methylmalonate-semial
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Aldh6a1-267M Recombinant Mouse Aldh6a1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human ALDH6A1-451H Recombinant Human ALDH6A1 Protein, GST-tagged Wheat Germ GST
    Human ALDH6A1-500H Recombinant Human aldehyde dehydrogenase 6 family, member A1, His-tagged E.coli His
    Human ALDH6A1-501H Recombinant Human Aldehyde Dehydrogenase 6 Family, Member A1, GST-tagged E.coli GST
    Human ALDH6A1-67H Recombinant Human ALDH6A1, His-tagged E.coli His
    Human ALDH6A1-8916HCL Recombinant Human ALDH6A1 293 Cell Lysate HEK293 N/A
    Mouse ALDH6A1-1532M Recombinant Mouse ALDH6A1 Protein Mammalian Cell His
    Zebrafish ALDH6A1-518Z Recombinant Zebrafish ALDH6A1 Mammalian Cell His

    ALDH6A1 involved in several pathways and played different roles in them. We selected most pathways ALDH6A1 participated on our site, such as Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Inositol phosphate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH6A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Valine, leucine and isoleucine degradation HMGCLL1; HIBADH; ALDH9A1B; PCCB; ACAA2; ALDH9A1; HMGCL; HIBCH; DLDH; AOX3L1
    beta-Alanine metabolism SRM; AOC2; ALDH2; ALDH6A1; MLYCD; HADHAB; GAD1B; ACADM; CNDP2; GAD1
    Inositol phosphate metabolism INPP5E; PLCD1A; NUDT4; SYNJ2; PI4KB; IPMKB; ALDH6A1; INPP4B; MTMR4; PIK3CG
    Propanoate metabolism DLDH; ECHDC1; MUT; ACAT1; PCCA; LDHAL6A; MCEE; BCKDHB; SUCLG2; ACACA
    Metabolic pathways CYP2C54; CYP2J5; CYP4A10; CERS1; ATP6V0A4; HLCS; NDUFC1; CYP2P7; RIMKLB; PC
    Carbon metabolism PKLR; GPIA; HADHAB; IDH3B; GOT1; ACADM; FBP2; PDHA1A; AMT; PSPH

    ALDH6A1 has several biochemical functions, for example, aldehyde dehydrogenase (NAD) activity, fatty-acyl-CoA binding, malonate-semialdehyde dehydrogenase (acetylating) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH6A1 itself. We selected most functions ALDH6A1 had, and list some proteins which have the same functions with ALDH6A1. You can find most of the proteins on our site.

    Function Related Protein
    aldehyde dehydrogenase (NAD) activity ALDH1A1; ALDH1B1; ALDH1L1; Aldh1a7; ALDH6A1; ALDH9A1A.1; ALDH7A1; ALDH3A2; ALDH9A1; ALDH3A2A
    fatty-acyl-CoA binding ACADVL; ACBD5; ALDH6A1; ACADM; GCDHB; SOAT1; ACAD8; ACOX3; ACBD4; ACAD11
    malonate-semialdehyde dehydrogenase (acetylating) activity ALDH6A1
    methylmalonate-semialdehyde dehydrogenase (acylating) activity ALDH6A1
    poly(A) RNA binding NGDN; RPS27A; RPS27.1; PTRH1; UBE2O; PRPF6; DHX8; RPS11; RPL8; DARS
    thiolester hydrolase activity ALDH6A1; ACOT5; ACNAT2; UFSP2; PPT2; Acnat1; UFSP1

    ALDH6A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDH6A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDH6A1.

    TRMT10C; LMO2; NDUFS7

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