Recombinant Human ALDH6A1 Protein, GST-tagged

• Cat.No.: ALDH6A1-451H
• Product Overview: Human ALDH6A1 full-length ORF ( AAH32371, 10 a.a. - 535 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 83.49 kDa
• AA Sequence: VRARILQVSSKVKSSPTWYSASSFS SSVPTVKLFIGGKFVESKSDKWIDI HNPATNEVIGRVPQATKAEMDAAIA SCKRAFPAWADTSVLSRQQVLLRYQ QLIKENLKEIAKLITLEQGKTLADA EGDVFRGLQVVEHACSVTSLMMGET MPSITKDMDLYSYRLPLGVCAGIAP FNFPAMIPLWMFPMAMVCGNTFLMK PSERVPGATMLLAKLLQDSGAPDGT LNIIHGQHEAVNFICDHPDIKAISF VGSNKAGEYIFERGSRHGKRVQANM GAKNHGVVMPDANKENTLNQLVGAA FGAAGQRCMALSTAVLVGEAKKWLP ELVEHAKNLRVNAGDQPGADLGPLI TPQAKERVCNLIDSGTKEGASILLD GRKIKVKGYENGNFVGPTIISNVKP NMTCYKEEIFGPVLVVLETETLDEA IQIVNNNPYGNGTAIFTTNGATARK YAHLVDVGQVGVNVPIPVPLPMFSF TGSRSSFRGDTNFYGKQGIQFYTQL KTITSQWKEEDATLSSPAVVMPTMG R
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALDH6A1 aldehyde dehydrogenase 6 family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH6A1
• Synonyms: ALDH6A1; aldehyde dehydrogenase 6 family, member A1; MMSDH; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; malonate-semialdehyde dehydrogenase; aldehyde dehydrogenase family 6 member A1; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSADHA; MGC40271
• Gene ID: 4329
• mRNA Refseq: NM_005589
• Protein Refseq: NP_005580
• MIM: 603178
• UniProt ID: Q02252