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ALOX12B

  • Official Full Name

    arachidonate 12-lipoxygenase, 12R type

  • Synonyms

    ALOX12B;arachidonate 12-lipoxygenase, 12R type;arachidonate 12-lipoxygenase, 12R-type;12R LOX;12R-lipoxygenase;epidermis-type lipoxygenase 12;12R-LOX;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ALOX12B-483H Recombinant Human ALOX12B Protein, GST-tagged Wheat Germ GST
Human ALOX12B-3608H Recombinant Human ALOX12B, His-tagged E.Coli or Yeast His 701
Human ALOX12B-7852H Recombinant Human ALOX12B protein, His & T7-tagged E.coli His/T7 Leu479~Ile701 (Accession # O75342)
Human ALOX12B-9590H Recombinant Human ALOX12B, GST-tagged E.coli GST 352-701a.a.
Human ALOX12B-8898HCL Recombinant Human ALOX12B 293 Cell Lysate HEK293 N/A
Human ALOX12B-1467HF Recombinant Full Length Human ALOX12B Protein, GST-tagged In Vitro Cell Free System GST 701 amino acids
Human ALOX12B-0445H Recombinant Human ALOX12B Protein (Leu479-Ile701), N-His-tagged E.coli N-His Leu479-Ile701
Mouse ALOX12B-1564M Recombinant Mouse ALOX12B Protein Mammalian Cell His
Mouse Alox12b-3609M Recombinant Mouse Alox12b, His-tagged E.Coli or Yeast His 701
Mouse Alox12b-7853M Recombinant Mouse Alox12b protein, His & T7-tagged E.coli His/T7 Glu389~Ile701 (Accession # O70582)
Mouse ALOX12B-481M Recombinant Mouse ALOX12B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ALOX12B-481M-B Recombinant Mouse ALOX12B Protein Pre-coupled Magnetic Beads HEK293
Rat ALOX12B-634R Recombinant Rat ALOX12B Protein Mammalian Cell His
Rat ALOX12B-290R-B Recombinant Rat ALOX12B Protein Pre-coupled Magnetic Beads HEK293
Rat ALOX12B-290R Recombinant Rat ALOX12B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ALOX12B involved in several pathways and played different roles in them. We selected most pathways ALOX12B participated on our site, such as Arachidonic acid metabolism, Metabolic pathways, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALOX12B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arachidonic acid metabolismCYP2C8;CYP4F11;PTGESL;CYP2P7;PTGES3;PLA2G4AA;CYP2C50;GPX1;PTGDSB
Metabolic pathwaysADH1C;HSD17B6;ADA;PTGS2A;EXT1C;MIBP2;GALNT2;PDXKA;NADKD1
Serotonergic synapseHTR2C;CYP4X1;CYP2J6;GABRB2;HTR1E;MAP2K1;ALOX5;CYP2D26;KRAS

ALOX12B has several biochemical functions, for example, arachidonate 12-lipoxygenase activity, iron ion binding, linoleate 9S-lipoxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALOX12B itself. We selected most functions ALOX12B had, and list some proteins which have the same functions with ALOX12B. You can find most of the proteins on our site.

Function Related Protein
arachidonate 12-lipoxygenase activityALOX15;ALOX12B;ALOX12;ALOX12E
iron ion bindingOGFOD2;CYP7A1;HBE1;CYP20A1;Scd1;CYP2E1;HBBE1.1;SC5DL;CYP3A25
linoleate 9S-lipoxygenase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenP4HA3;ALOX8;ALOX12E;TMLHE;ADOA;ALOX12;ADOB;ALOX5A;ALOX5B.3
protein bindingRPUSD3;FBXW9;RAC3;GFI1;MCM3;MYOZ2;G3BP1;UQCRB;SIX3

ALOX12B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALOX12B here. Most of them are supplied by our site. Hope this information will be useful for your research of ALOX12B.

ALOXE3; TGM1

  • Q&As
  • Reviews

Q&As (16)

Ask a question
How does ALOX12B gene mutation affect cardiovascular health? 02/22/2023

Mutations in the ALOX12B gene may lead to the development of cardiovascular disease, which can affect cardiovascular health.

Are ALOX12B gene variants associated with tumors? 02/20/2023

The ALOX12B gene variant has not been shown to be associated with tumors.

Based on the mutation of ALOX12B gene, is there an effective treatment at present? 12/18/2022

There is no specific treatment for the ALOX12B gene mutation. Treatment is mostly based on symptom relief and reduction of disease progression.

How is the ALOX12B gene mutant diagnosed? 08/02/2022

A mutation of the ALOX12B gene can be diagnosed with a genetic test or blood test.

What is the regulatory mechanism of ALOX12B gene? 05/12/2021

The regulatory mechanisms of ALOX12B gene include transcription factors, miRNA and other regulatory mechanisms.

Does ALOX12B gene mutation have an impact on skin health? 04/18/2021

Mutations in the ALOX12B gene may lead to the development of skin diseases that affect skin health.

Does ALOX12B gene mutation cause liver disease? 02/24/2021

ALOX12B gene mutation and liver disease has not been proven to have a clear link.

In which populations is the ALOX12B gene most common? 10/11/2020

Current studies have shown that the ALOX12B variant is more common in Asian populations.

What is the function of the ALOX12B gene? 08/23/2020

ALOX12B encodes the 12R-LOX enzyme, which is involved in biological processes such as lipid metabolism and inflammatory responses.

How do polymorphisms in the ALOX12B gene affect its function? 06/20/2020

The polymorphism of ALOX12B gene can affect the activity of the enzyme it encodes, and thus affect related biological processes.

Is the SNP of ALOX12B gene related to drug metabolism? 03/08/2020

The SNP of ALOX12B gene has not been confirmed to have a clear association with drug metabolism.

Does ALOX12B affect the immune system? 12/09/2019

The ALOX12B gene plays an important role in the body's inflammatory response and therefore may influence the function of the immune system.

Which diseases are related to the expression of ALOX12B gene? 09/26/2019

Mutations in the ALOX12B gene have been linked to skin disorders, asthma, cardiovascular disease and more.

Does ALOX12B gene affect body metabolism? 09/09/2019

The ALOX12B gene can affect biological processes such as fat metabolism in the body, thus affecting body metabolism.

Which diseases are the ALOX12B gene mutations clearly associated with? 07/01/2019

A mutant version of the ALOX12B gene has been linked to a rare inherited fat metabolism disorder called Allen's syndrome.

In which organs is ALOX12B gene more expressed? 06/24/2019

ALOX12B gene is more expressed in skin, liver, heart, kidney and other organs.

Customer Reviews (3)

Write a review
Reviews
06/22/2022

    ALOX12B has good absorbability and high bioavailability.

    01/29/2021

      Highly effective in signal transduction pathways.

      08/20/2020

        Under different environmental conditions,ALOX12B showed good stability.

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