ALOX12B
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Official Full Name
arachidonate 12-lipoxygenase, 12R type
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Synonyms
ALOX12B;arachidonate 12-lipoxygenase, 12R type;arachidonate 12-lipoxygenase, 12R-type;12R LOX;12R-lipoxygenase;epidermis-type lipoxygenase 12;12R-LOX;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- E.Coli or Yeast
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ALOX12B-483H | Recombinant Human ALOX12B Protein, GST-tagged | Wheat Germ | GST | ||
Human | ALOX12B-3608H | Recombinant Human ALOX12B, His-tagged | E.Coli or Yeast | His | 701 | |
Human | ALOX12B-7852H | Recombinant Human ALOX12B protein, His & T7-tagged | E.coli | His/T7 | Leu479~Ile701 (Accession # O75342) | |
Human | ALOX12B-9590H | Recombinant Human ALOX12B, GST-tagged | E.coli | GST | 352-701a.a. | |
Human | ALOX12B-8898HCL | Recombinant Human ALOX12B 293 Cell Lysate | HEK293 | N/A | ||
Human | ALOX12B-1467HF | Recombinant Full Length Human ALOX12B Protein, GST-tagged | In Vitro Cell Free System | GST | 701 amino acids | |
Human | ALOX12B-0445H | Recombinant Human ALOX12B Protein (Leu479-Ile701), N-His-tagged | E.coli | N-His | Leu479-Ile701 | |
Mouse | ALOX12B-1564M | Recombinant Mouse ALOX12B Protein | Mammalian Cell | His | ||
Mouse | Alox12b-3609M | Recombinant Mouse Alox12b, His-tagged | E.Coli or Yeast | His | 701 | |
Mouse | Alox12b-7853M | Recombinant Mouse Alox12b protein, His & T7-tagged | E.coli | His/T7 | Glu389~Ile701 (Accession # O70582) | |
Mouse | ALOX12B-481M | Recombinant Mouse ALOX12B Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ALOX12B-481M-B | Recombinant Mouse ALOX12B Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | ALOX12B-634R | Recombinant Rat ALOX12B Protein | Mammalian Cell | His | ||
Rat | ALOX12B-290R-B | Recombinant Rat ALOX12B Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | ALOX12B-290R | Recombinant Rat ALOX12B Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
- Involved Pathway
- Protein Function
- Interacting Protein
ALOX12B involved in several pathways and played different roles in them. We selected most pathways ALOX12B participated on our site, such as Arachidonic acid metabolism, Metabolic pathways, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALOX12B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Arachidonic acid metabolism | PTGS2B;CYP2J6;PTGS1;GPX6;PTGES;PTGDSB;GPX7;CYP2AD3;PLA2G4F |
Metabolic pathways | ITPKA;DPAGT1;CYP3A7-CYP3AP1;C1GALT1B;CKMT1A;ALG10B;NADKD1;AGMAT;EXTL3 |
Serotonergic synapse | GNG3;CYP4X1;PTGS2;GNAO1;ALOX15B;HTR1E;PLCB3;MAPK3;PLA2G4C |
ALOX12B has several biochemical functions, for example, arachidonate 12-lipoxygenase activity, iron ion binding, linoleate 9S-lipoxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALOX12B itself. We selected most functions ALOX12B had, and list some proteins which have the same functions with ALOX12B. You can find most of the proteins on our site.
Function | Related Protein |
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arachidonate 12-lipoxygenase activity | ALOX12;ALOX12E;ALOX15;ALOX12B |
iron ion binding | CYP4F22;NOS2;CYP2J2;CYP2AA8;HBA1;TYW1;CYP3C1;CYP2D26;PHF8 |
linoleate 9S-lipoxygenase activity | |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | ADOB;ADOA;P4HA1A;ALOX5A;P4HA3;P4HA1B;ALOX12E;ALOX5B.2;ALOX5B.3 |
protein binding | PAWR;AAAS;HINT2;P4HA3;ZNF559-ZNF177;SH2D1A;TRIP6;LACTB2;SH2D2A |
ALOX12B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALOX12B here. Most of them are supplied by our site. Hope this information will be useful for your research of ALOX12B.
ALOXE3; TGM1
- Q&As
- Reviews
Q&As (16)
Ask a questionMutations in the ALOX12B gene may lead to the development of cardiovascular disease, which can affect cardiovascular health.
The ALOX12B gene variant has not been shown to be associated with tumors.
There is no specific treatment for the ALOX12B gene mutation. Treatment is mostly based on symptom relief and reduction of disease progression.
A mutation of the ALOX12B gene can be diagnosed with a genetic test or blood test.
The regulatory mechanisms of ALOX12B gene include transcription factors, miRNA and other regulatory mechanisms.
Mutations in the ALOX12B gene may lead to the development of skin diseases that affect skin health.
ALOX12B gene mutation and liver disease has not been proven to have a clear link.
Current studies have shown that the ALOX12B variant is more common in Asian populations.
ALOX12B encodes the 12R-LOX enzyme, which is involved in biological processes such as lipid metabolism and inflammatory responses.
The polymorphism of ALOX12B gene can affect the activity of the enzyme it encodes, and thus affect related biological processes.
The SNP of ALOX12B gene has not been confirmed to have a clear association with drug metabolism.
The ALOX12B gene plays an important role in the body's inflammatory response and therefore may influence the function of the immune system.
Mutations in the ALOX12B gene have been linked to skin disorders, asthma, cardiovascular disease and more.
The ALOX12B gene can affect biological processes such as fat metabolism in the body, thus affecting body metabolism.
A mutant version of the ALOX12B gene has been linked to a rare inherited fat metabolism disorder called Allen's syndrome.
ALOX12B gene is more expressed in skin, liver, heart, kidney and other organs.
Customer Reviews (3)
Write a reviewALOX12B has good absorbability and high bioavailability.
Highly effective in signal transduction pathways.
Under different environmental conditions,ALOX12B showed good stability.
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