Recombinant Human ALOX12B, His-tagged

• Cat.No.: ALOX12B-3608H
• Product Overview: Arachidonate 12-lipoxygenase, 12R-type (ALOX12B)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 701
• Description: This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of ALOX12B recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ALOX12B arachidonate 12-lipoxygenase, 12R type [ Homo sapiens ]
• Official Symbol: ALOX12B
• Synonyms: ALOX12B; arachidonate 12-lipoxygenase, 12R type; arachidonate 12-lipoxygenase, 12R-type; 12R LOX; 12R-lipoxygenase; epidermis-type lipoxygenase 12; 12R-LOX
• Gene ID: 242
• mRNA Refseq: NM_001139
• Protein Refseq: NP_001130
• MIM: 603741
• UniProt ID: O75342
• Chromosome Location: 17p13.1
• Pathway: Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; IL23-mediated signaling events, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Serotonergic synapse, organism-specif
• Function: arachidonate 12-lipoxygenase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity