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AMDHD2

  • Official Full Name

    amidohydrolase domain containing 2

  • Synonyms

    AMDHD2; amidohydrolase domain containing 2; putative N-acetylglucosamine-6-phosphate deacetylase; CGI 14; Amidohydrolase domain containing protein 2; Amidohydrolase domain-containing protein 2; CGI14; GlcNAc 6-P deacetylase; NAGA_HUMAN; CGI-14;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AMDHD2-518H Recombinant Human AMDHD2 protein, GST-tagged Wheat Germ GST
Human AMDHD2-8884HCL Recombinant Human AMDHD2 293 Cell Lysate HEK293 N/A
Human AMDHD2-1229HF Recombinant Full Length Human AMDHD2 Protein, GST-tagged In Vitro Cell Free System GST 439 amino acids
Mouse AMDHD2-1594M Recombinant Mouse AMDHD2 Protein Mammalian Cell His
Mouse AMDHD2-504M Recombinant Mouse AMDHD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse AMDHD2-504M-B Recombinant Mouse AMDHD2 Protein Pre-coupled Magnetic Beads HEK293
Rat AMDHD2-648R Recombinant Rat AMDHD2 Protein Mammalian Cell His
Rat AMDHD2-304R Recombinant Rat AMDHD2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat AMDHD2-304R-B Recombinant Rat AMDHD2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish AMDHD2-11704Z Recombinant Zebrafish AMDHD2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • AMDHD2 Related Articles

AMDHD2 involved in several pathways and played different roles in them. We selected most pathways AMDHD2 participated on our site, such as Amino sugar and nucleotide sugar metabolism, Biosynthesis of antibiotics, N-acetylglucosamine degradation I, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMDHD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amino sugar and nucleotide sugar metabolismCYB5R3;UGP2;CYB5RL;NANP;UGDH;GMPPA;PGM1;GPIA;CHIA
Biosynthesis of antibioticsDAO1;CTH;CMBL;PAICS;AK7;ECHS1;AKR1A1;CS;LDHAL6A
N-acetylglucosamine degradation IGNPDA2;GNPDA1;AMDHD2
N-acetylglucosamine degradation IIGNPDA1;GNPDA2;AMDHD2

AMDHD2 has several biochemical functions, for example, N-acetylglucosamine-6-phosphate deacetylase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMDHD2 itself. We selected most functions AMDHD2 had, and list some proteins which have the same functions with AMDHD2. You can find most of the proteins on our site.

Function Related Protein
N-acetylglucosamine-6-phosphate deacetylase activity
metal ion bindingLONRF1L;SETDB1B;CACNA1D;ARIH1L;RXRBB;FGD6;AMPD1;ZFP524;GPR39
protein bindingGTF2E1;SNAPC3;CDC27;SUMO1;CA4;FAM46C;DLA;HMGB1;FASTK

AMDHD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMDHD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AMDHD2.

TRIP13; GNPDA2; purL

Fedorov, AA; Marti-Arbona, R; et al. Structure of N-Formimino-L-glutamate lminohydrolase from Pseudomonas aeruginosa. BIOCHEMISTRY 54:890-897(2015).
Dobritzsch, D; Wang, HM; et al. Structural and functional characterization of ochratoxinase, a novel mycotoxin-degrading enzyme. BIOCHEMICAL JOURNAL 462:441-452(2014).
  • Q&As
  • Reviews

Q&As (10)

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What are the downstream signaling pathways or cellular processes influenced by AMDHD2 activity? 10/15/2022

AMDHD2 activity can influence downstream signaling pathways involved in cell proliferation, differentiation, or stress responses, impacting cellular metabolism, growth, or survival.

What is the subcellular localization of AMDHD2 and its significance in cellular processes? 06/04/2021

AMDHD2 exhibits a specific subcellular localization, such as in the cytoplasm or mitochondria, which is crucial for its involvement in nucleotide metabolism or other related processes.

How does AMDHD2 participate in cellular energy metabolism and the regulation of metabolic pathways? 03/16/2021

AMDHD2 contributes to cellular energy metabolism by influencing the utilization of nucleotide-derived metabolites in energy production pathways, such as mitochondrial respiration or ATP synthesis.

How does AMDHD2 contribute to nucleotide metabolism and what are the implications for cellular physiology? 08/15/2020

AMDHD2 plays a role in nucleotide metabolism, contributing to the biosynthesis, salvage, or recycling of nucleotides, which are essential for DNA synthesis, RNA transcription, and cellular signaling.

Can targeting AMDHD2 activity or expression provide potential therapeutic strategies for metabolic disorders or cancer? 01/14/2020

Modulating AMDHD2 activity or expression may hold therapeutic potential for metabolic disorders, such as nucleotide metabolism-related diseases or cancer, providing opportunities for developing targeted interventions or personalized therapies.

What is the role of AMDHD2 in DNA damage repair and genome stability maintenance? 11/23/2019

AMDHD2 is involved in DNA damage repair mechanisms, participating in the removal or repair of damaged nucleotides or DNA lesions, thus maintaining genome stability.

What are the enzymatic activities of AMDHD2 and its substrate specificity? 10/23/2019

AMDHD2 possesses enzymatic activities, such as phosphatase or hydrolase activity, and exhibits substrate specificity towards specific nucleotide derivatives or metabolic intermediates.

How does AMDHD2 deficiency or overexpression affect cellular proliferation, differentiation, or disease progression? 10/08/2019

AMDHD2 deficiency or dysregulation may lead to impaired nucleotide metabolism, DNA repair defects, altered cellular proliferation, or increased susceptibility to certain diseases, including cancer.

What are the molecular interactions of AMDHD2 with other proteins and their functional consequences? 07/10/2019

AMDHD2 interacts with other proteins involved in nucleotide metabolism, DNA repair, or cellular signaling, and these interactions modulate processes such as nucleotide synthesis, repair, or cell cycle progression.

How is AMDHD2 expression regulated under different cellular conditions or in response to metabolic cues? 04/24/2019

AMDHD2 expression is regulated at transcriptional and post-transcriptional levels, influenced by cellular signals, metabolic cues, or growth factor signaling pathways.

Customer Reviews (3)

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Reviews
12/14/2021

    Enhanced signal stability for prolonged imaging experiments.

    11/08/2019

      Low assay interference from interfering substances.

      03/04/2018

        Consistent detection of protein post-translational modifications.

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