AMDHD2
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Official Full Name
amidohydrolase domain containing 2
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Synonyms
AMDHD2; amidohydrolase domain containing 2; putative N-acetylglucosamine-6-phosphate deacetylase; CGI 14; Amidohydrolase domain containing protein 2; Amidohydrolase domain-containing protein 2; CGI14; GlcNAc 6-P deacetylase; NAGA_HUMAN; CGI-14;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | AMDHD2-518H | Recombinant Human AMDHD2 protein, GST-tagged | Wheat Germ | GST | ||
Human | AMDHD2-8884HCL | Recombinant Human AMDHD2 293 Cell Lysate | HEK293 | N/A | ||
Human | AMDHD2-1229HF | Recombinant Full Length Human AMDHD2 Protein, GST-tagged | In Vitro Cell Free System | GST | 439 amino acids | |
Mouse | AMDHD2-1594M | Recombinant Mouse AMDHD2 Protein | Mammalian Cell | His | ||
Mouse | AMDHD2-504M | Recombinant Mouse AMDHD2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | AMDHD2-504M-B | Recombinant Mouse AMDHD2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | AMDHD2-648R | Recombinant Rat AMDHD2 Protein | Mammalian Cell | His | ||
Rat | AMDHD2-304R | Recombinant Rat AMDHD2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | AMDHD2-304R-B | Recombinant Rat AMDHD2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | AMDHD2-11704Z | Recombinant Zebrafish AMDHD2 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- AMDHD2 Related Articles
AMDHD2 involved in several pathways and played different roles in them. We selected most pathways AMDHD2 participated on our site, such as Amino sugar and nucleotide sugar metabolism, Biosynthesis of antibiotics, N-acetylglucosamine degradation I, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMDHD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Amino sugar and nucleotide sugar metabolism | CYB5R3;UGP2;CYB5RL;NANP;UGDH;GMPPA;PGM1;GPIA;CHIA |
Biosynthesis of antibiotics | DAO1;CTH;CMBL;PAICS;AK7;ECHS1;AKR1A1;CS;LDHAL6A |
N-acetylglucosamine degradation I | GNPDA2;GNPDA1;AMDHD2 |
N-acetylglucosamine degradation II | GNPDA1;GNPDA2;AMDHD2 |
AMDHD2 has several biochemical functions, for example, N-acetylglucosamine-6-phosphate deacetylase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMDHD2 itself. We selected most functions AMDHD2 had, and list some proteins which have the same functions with AMDHD2. You can find most of the proteins on our site.
Function | Related Protein |
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N-acetylglucosamine-6-phosphate deacetylase activity | |
metal ion binding | LONRF1L;SETDB1B;CACNA1D;ARIH1L;RXRBB;FGD6;AMPD1;ZFP524;GPR39 |
protein binding | GTF2E1;SNAPC3;CDC27;SUMO1;CA4;FAM46C;DLA;HMGB1;FASTK |
AMDHD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMDHD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AMDHD2.
TRIP13; GNPDA2; purL
- Q&As
- Reviews
Q&As (10)
Ask a questionAMDHD2 activity can influence downstream signaling pathways involved in cell proliferation, differentiation, or stress responses, impacting cellular metabolism, growth, or survival.
AMDHD2 exhibits a specific subcellular localization, such as in the cytoplasm or mitochondria, which is crucial for its involvement in nucleotide metabolism or other related processes.
AMDHD2 contributes to cellular energy metabolism by influencing the utilization of nucleotide-derived metabolites in energy production pathways, such as mitochondrial respiration or ATP synthesis.
AMDHD2 plays a role in nucleotide metabolism, contributing to the biosynthesis, salvage, or recycling of nucleotides, which are essential for DNA synthesis, RNA transcription, and cellular signaling.
Modulating AMDHD2 activity or expression may hold therapeutic potential for metabolic disorders, such as nucleotide metabolism-related diseases or cancer, providing opportunities for developing targeted interventions or personalized therapies.
AMDHD2 is involved in DNA damage repair mechanisms, participating in the removal or repair of damaged nucleotides or DNA lesions, thus maintaining genome stability.
AMDHD2 possesses enzymatic activities, such as phosphatase or hydrolase activity, and exhibits substrate specificity towards specific nucleotide derivatives or metabolic intermediates.
AMDHD2 deficiency or dysregulation may lead to impaired nucleotide metabolism, DNA repair defects, altered cellular proliferation, or increased susceptibility to certain diseases, including cancer.
AMDHD2 interacts with other proteins involved in nucleotide metabolism, DNA repair, or cellular signaling, and these interactions modulate processes such as nucleotide synthesis, repair, or cell cycle progression.
AMDHD2 expression is regulated at transcriptional and post-transcriptional levels, influenced by cellular signals, metabolic cues, or growth factor signaling pathways.
Customer Reviews (3)
Write a reviewEnhanced signal stability for prolonged imaging experiments.
Low assay interference from interfering substances.
Consistent detection of protein post-translational modifications.
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