arhgap1
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  • Official Full Name
  • Rho GTPase activating protein 1
  • Background
  • Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the ARHGAP1 gene.
  • Synonyms
  • ARHGAP1; Rho GTPase activating protein 1; rho GTPase-activating protein 1; Cdc42GAP; p50rhoGAP; RhoGAP; ARHGAP 1; CDC42 GTPase activating protein; GTPase activating protein rhoOGAP; OTTHUMP00000233485; OTTHUMP00000233486; p50 RhoGAP; Rho related small GTPase protein activator; Rho type GTPase activating protein 1; RHOGAP1; p50-RhoGAP; CDC42 GTPase-activating protein; GTPase-activating protein rhoOGAP; rho-type GTPase-activating protein 1; rho-related small GTPase protein activator
Cat.#:ARHGAP1-36HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARHGAP1 protein, GST-tagged
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Cat.#:ARHGAP1-9812HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARHGAP1, GST-tagged
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Cat.#:ARHGAP1-387RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ARHGAP1 Protein, His-tagged
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Cat.#:ARHGAP1-2523ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ARHGAP1
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Cat.#:ARHGAP1-8745HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ARHGAP1 293 Cell Lysate
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Involved Pathway

ARHGAP1 involved in several pathways and played different roles in them. We selected most pathways ARHGAP1 participated on our site, such as Regulation of CDC42 activity, Regulation of RAC1 activity, Rho GTPase cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Regulation of CDC42 activity
SPATA13; DOCK10; ARHGEF25; ARHGAP17; DOCK9; DNMBP; MCF2L; BCAR3; DOCK6; ARHGAP1
Regulation of RAC1 activity
RAP1GDS1; ABR; ARHGAP17; RALBP1; ARHGAP1; DEF6; ARHGEF25; CHN2; CHN1; DOCK6
Rho GTPase cycle
ARHGAP4; ARHGEF18; ABR; ARHGAP44; RHOUA; ARAP2; AKAP13; FGD4A; GMIP; FGD4
Signal Transduction
TAAR1; KREMEN2; FGFBP2; ARHGAP23; JUPA; RGS1; OXGR1; ARHGAP19; OR56A1; MYO9B
Signaling by Rho GTPases
ARHGEF16; FAM13B; ARHGAP6; RHOF; ARHGAP1; ARHGAP11A; RHOV; CHN2; ARHGAP28; ARHGAP12B

Protein Function

ARHGAP1 has several biochemical functions, for example, GTPase activator activity, SH3 domain binding, SH3/SH2 adaptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP1 itself. We selected most functions ARHGAP1 had, and list some proteins which have the same functions with ARHGAP1. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activator activity
Related Protein ARHGAP19; ARHGAP9; PREX2; STARD8; CHN2; SIPA1L1; RIN3; RGS3A; RGS18; USP6NL
Function SH3 domain binding
Related Protein SHANK1; ITGB1BP2; TOM1L1; SH3BGRL; SH3BP2; EFS; CNTNAP1; NCF1; OSTF1; CYBA
Function SH3/SH2 adaptor activity
Related Protein SH2D2A; CHN2; SH2D3A; CD28; SKAP2; FCRL2; ARHGAP4; NCK1; GRB7; HSH2D
Function protein binding
Related Protein DUSP26; BTF3L4; TADA3; DUT; AKT3; PBX1; C1orf50; TGOLN2; LIMS3L; VIPR1

Interacting Protein

ARHGAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP1.
CDC42; RHOA; CDC42; CHEK2; RHOC; AGTRAP; q8d0i9_yerpe; pi3p; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate; ere_dna; STK4

ARHGAP1 Related Articles

Jarius, S; Scharf, M; et al. Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia. Journal of Neuroinflammation 11:-(2014).
Navarrete-Perea, J; Moguel, B; et al. Identification and quantification of host proteins in the vesicular fluid of porcine Taenia solium cysticerci. EXPERIMENTAL PARASITOLOGY 143:11-17(2014).