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ARHGAP21

  • Official Full Name

    Rho GTPase activating protein 21

  • Synonyms

    ARHGAP21;Rho GTPase activating protein 21;23725;ENSG00000107863;ARHGAP10;10p12.1;10p12.3;FLJ33323, FLJ90108, DKFZp761L0424;rho GTPase-activating protein 21;rho GTPase-activating protein 21;Rho-GTPase activating protein 10;rho GTPase-activating protein 10;rho-type GTPase-activating protein 21;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Rhesus Macaque ARHGAP21-391R Recombinant Rhesus monkey ARHGAP21 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ARHGAP21-220R Recombinant Rhesus Macaque ARHGAP21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ARHGAP21-220R-B Recombinant Rhesus Macaque ARHGAP21 Protein Pre-coupled Magnetic Beads HEK293
Chicken ARHGAP21-4081C Recombinant Chicken ARHGAP21 Mammalian Cell His
  • ARHGAP21 Related Articles

ARHGAP21 involved in several pathways and played different roles in them. We selected most pathways ARHGAP21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ARHGAP21 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP21 itself. We selected most functions ARHGAP21 had, and list some proteins which have the same functions with ARHGAP21. You can find most of the proteins on our site.

Function Related Protein

ARHGAP21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP21 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP21.

Xavier, JM; Ricon, L; et al. Arhgap21 Expression in Bone Marrow Niche Is Crucial for Hematopoietic Progenitor Homing and Short Term Reconstitution after Transplantation. BLOOD 124:-(2014).
Xavier, JM; Lauremlia, R; et al. Arhgap21(+/-) Mice Show Impaired Adhesion, Migration, Homing and Short Term Reconstitution of Hematopoietic Progenitor Cells. BLOOD 124:-(2014).
  • Q&As
  • Reviews

Q&As (7)

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Are there any diseases associated with ARHGAP21 dysfunction? 04/22/2023

Currently, there are no specific diseases or disorders directly linked to ARHGAP21 dysfunction. However, its role in regulating Rho GTPases suggests that dysregulation of ARHGAP21 may contribute to pathological conditions involving abnormal cytoskeletal organization, cell migration, or adhesion. Further research is necessary to explore potential disease associations.

Is ARHGAP21 involved in cancer? 10/02/2020

Limited research has been conducted on the role of ARHGAP21 in cancer. Some studies have suggested that ARHGAP21 may have tumor-suppressive properties and could potentially inhibit tumor growth and metastasis. However, more research is needed to fully understand the implications of ARHGAP21 in cancer biology.

How is ARHGAP21 implicated in neuronal development? 05/14/2020

ARHGAP21 is abundantly expressed in the brain, suggesting its involvement in neuronal development. Research indicates that ARHGAP21 may play a role in neurite outgrowth and pathfinding during the formation of neural circuits. Through its regulation of Rho GTPases, ARHGAP21 influences cytoskeletal dynamics, which are crucial for proper neuronal growth and connectivity.

Are there any post-translational modifications of ARHGAP21? 12/15/2019

Limited information is available regarding post-translational modifications of ARHGAP21. However, it has been reported that ARHGAP21 can undergo phosphorylation at specific serine and threonine residues. These modifications potentially regulate its activity and protein-protein interactions.

Can ARHGAP21 interact with other proteins? 12/02/2019

Yes, ARHGAP21 can interact with several proteins within the cell. It is known to interact with various Rho GTPases, as well as other signaling proteins involved in cytoskeletal dynamics and cellular adhesion. These interactions contribute to the regulatory functions of ARHGAP21 in cellular processes.

Is ARHGAP21 associated with any genetic disorders? 10/10/2016

Currently, there are no known genetic disorders directly linked to ARHGAP21 mutations or dysregulation. However, as research on ARHGAP21 advances, it is possible that genetic variations in ARHGAP21 could be identified and associated with certain diseases or disorders. Continued investigation is required to determine any such associations.

Can ARHGAP21 be targeted for therapeutics? 06/02/2016

The therapeutic potential of targeting ARHGAP21 is yet to be explored extensively. However, considering its regulatory role in Rho GTPases, which are implicated in various diseases, modulating ARHGAP21 activity could be a possible avenue for therapeutic intervention. Further studies are needed to evaluate the feasibility and effectiveness of targeting ARHGAP21 in specific pathological conditions.

Customer Reviews (8)

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Reviews
04/22/2023

    This high-quality protein is crucial for the success of my experiments, ensuring that I obtain reliable and meaningful scientific findings.

    10/24/2022

      By actively engaging with researchers and understanding their needs, manufacturers can contribute significantly to the success and impact of research involving the ARHGAP21 protein.

      01/01/2021

        Manufacturers with the capacity for bulk production can offer ARHGAP21 protein in larger quantities, which is advantageous for researchers working on large-scale experiments or collaborations.

        12/10/2020

          Manufacturers can provide comprehensive product information, including data on the functionality, stability, and handling of ARHGAP21 protein.

          05/14/2020

            Their team of experts is not only knowledgeable about the ARHGAP21 protein but is also dedicated to assisting researchers like myself in overcoming any challenges that may arise.

            03/11/2020

              bulk production often leads to economies of scale, making the ARHGAP21 protein more cost-effective for research budgets.

              12/15/2019

                Whether it's modifying protocols, providing custom formulations, or offering personalized recommendations, their flexibility ensures that I have the necessary tools to carry out my experiments seamlessly.

                12/02/2019

                  the manufacturer's dedication to continuous improvement and innovation is evident in their ongoing efforts to enhance the ARHGAP21 protein's performance and optimize its applications.

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