ARHGAP27 Protein, Rho GTPase activating protein 27


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Official Full Name Rho GTPase activating protein 27
Background Rho (see ARHA; MIM 165390)-like small GTPases are involved in many cellular processes, and they are inactive in the;GDP-bound state and active in the GTP-bound state. GTPase-activating proteins, such as ARHGAP27, inhibit Rho-like;proteins by stimulating their intrinsic GTPase activity (Katoh and Katoh, 2004 (PubMed 15492870)).
Synonyms ARHGAP27; Rho GTPase activating protein 27; SH3 domain containing 20 , SH3D20; rho GTPase-activating protein 27; CAMGAP1; FLJ43547; SH3P20; SH3 domain containing 20; SH3 domain-containing protein 20; rho-type GTPase-activating protein 27; CIN85-associated
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARHGAP27-8740HCL Recombinant Human ARHGAP27 293 Cell Lysate HEK293 N/A
    Mouse ARHGAP27-1866M Recombinant Mouse ARHGAP27 Protein Mammalian Cell His
    Rat ARHGAP27-766R Recombinant Rat ARHGAP27 Protein Mammalian Cell His

    ARHGAP27 involved in several pathways and played different roles in them. We selected most pathways ARHGAP27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    ARHGAP27 has several biochemical functions, for example, GTPase activator activity, SH3 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP27 itself. We selected most functions ARHGAP27 had, and list some proteins which have the same functions with ARHGAP27. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity CHN1; DOCK4; ELMOD2; MURC; RGS13; ARAP1; ELMOD1; ARHGAP17; AGFG1A; GRTP1A
    SH3 domain binding DENND1A; ARHGAP1; SHANK3; PAK3; TOM1L1; UVRAG; PLSCR4; SIRPA; EFS; QKI2

    ARHGAP27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP27 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP27.


    Connelly, TM; Berg, AS; et al. T-cell activation Rho GTPase-activating protein expression varies with inflammation location and severity in Crohn's disease. JOURNAL OF SURGICAL RESEARCH 190:457-464(2014).
    Au, SLK; Wong, CCL; et al. EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers. PLOS ONE 8:-(2013).

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