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ARHGAP44

  • Official Full Name

    Rho GTPase activating protein 44

  • Synonyms

    ARHGAP44; Rho GTPase activating protein 44; rho GTPase-activating protein 44; KIAA0672; RICH 2; RICH2; RICH-2; rho GTPase-activating protein RICH2; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2; NPC-A-10;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ARHGAP44-1278H Recombinant Human ARHGAP44 Mammalian Cell His
Human ARHGAP44-771H Recombinant Human ARHGAP44 protein, GST-tagged Wheat Germ GST
Human ARHGAP44-2494H-B Recombinant Human ARHGAP44 Protein Pre-coupled Magnetic Beads HEK293
Human ARHGAP44-1090HF Recombinant Full Length Human ARHGAP44 Protein, GST-tagged In Vitro Cell Free System GST 818 amino acids
Human ARHGAP44-2494H Recombinant Human ARHGAP44 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ARHGAP44-1878M Recombinant Mouse ARHGAP44 Protein Mammalian Cell His
Mouse ARHGAP44-685M Recombinant Mouse ARHGAP44 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ARHGAP44-685M-B Recombinant Mouse ARHGAP44 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ARHGAP44 involved in several pathways and played different roles in them. We selected most pathways ARHGAP44 participated on our site, such as Rho GTPase cycle, Signal Transduction, Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP44 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rho GTPase cycleARHGAP11A;ARAP2;ARHGAP33;ARHGAP32;TAGAPA;ARHGAP1;GMIP;FAM13B;RHOT1B
Signal TransductionC;ADH8B;TTC21B;GPR37L1;IGF2BP1;FGD4A;TNKS2;CSHL1;CRABP1
Signaling by Rho GTPasesTAGAP1;RHOT2;NOXO1;RHOT1;IQGAP3;RHPN1;PRC1;MKL1B;RHOF

ARHGAP44 has several biochemical functions, for example, GTPase activator activity, phospholipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP44 itself. We selected most functions ARHGAP44 had, and list some proteins which have the same functions with ARHGAP44. You can find most of the proteins on our site.

Function Related Protein
GTPase activator activityARHGAP23;TBC1D10B;RGS21;ASAP1A;ARHGAP17;ARHGAP42;RASA1;ARHGAP20;ADAP2
phospholipid bindingSYTL4;SPTB;NBEAA;ANXA1;OSBPL1A;ANXA9;PICALMA;NBEAL2;DAPP1
protein bindingPDP1;NFKB1;UNC119B;CBY1;AAAS;RAB11FIP2;LIMA1;UCHL1;TBKBP1

ARHGAP44 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP44 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP44.

HN1

  • Q&As
  • Reviews

Q&As (8)

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Are there any animal models available for studying ARHGAP44? 11/11/2022

Currently, there are no established animal models specifically targeting ARHGAP44. Creating animal models, such as transgenic or knockout mice, can provide valuable insights into the biological role of ARHGAP44 and its potential implications in various physiological processes or diseases.

Are there any known interacting partners of ARHGAP44? 05/18/2022

The known interacting partners of ARHGAP44 have not been extensively characterized. Large-scale protein interaction studies or specific experimental assays may be required to identify and validate potential binding partners or downstream effectors of ARHGAP44.

Are there any known mutations or genetic variants in ARHGAP44 associated with diseases or disorders? 05/04/2021

As of now, there is no known association between mutations or genetic variants in ARHGAP44 and specific diseases or disorders. This field of research is still in its early stages, and further studies are needed to explore potential links between ARHGAP44 and human pathologies.

Is ARHGAP44 expressed in specific tissues or organs? 12/06/2020

The tissue-specific expression pattern of ARHGAP44 has not been extensively investigated. However, publicly available gene expression databases can provide limited information on its expression levels across different tissues and cell types. Further research using techniques such as quantitative PCR or immunohistochemistry can provide more accurate and detailed information on its tissue-specific expression.

What are the possible implications of ARHGAP44 dysfunction? 12/11/2018

The precise implications of ARHGAP44 dysfunction are currently unknown due to limited research on this protein. However, given its potential involvement in regulating cytoskeletal dynamics and cell migration, dysfunctional ARHGAP44 may potentially contribute to abnormalities in these processes, leading to developmental disorders or diseases characterized by aberrant cell motility. Further studies are necessary to unravel its functional consequences.

Is ARHGAP44 implicated in any signaling pathways? 07/08/2018

At present, no specific signaling pathways have been identified in which ARHGAP44 is known to be involved. Further research is essential to explore its potential interactions with other proteins or components of signaling cascades.

Are there any known domains or motifs in ARHGAP44? 05/10/2016

ARHGAP44 contains a conserved RhoGAP domain, which is commonly found in GAP proteins and is responsible for catalyzing the hydrolysis of GTP bound to Rho GTPases. This domain suggests that ARHGAP44 may specifically target and inactivate Rho GTPases.

Has the expression or activity of ARHGAP44 been regulated or modulated? 04/25/2016

The regulation of ARHGAP44 expression and activity remains poorly understood. More studies are required to investigate the mechanisms that control its expression, potential post-translational modifications, or any regulatory factors that may impact its activity.

Customer Reviews (8)

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Reviews
12/08/2021

    ARHGAP44 protein is an enzyme involved in the digestion of carbohydrates, specifically starch.

    09/17/2021

      A reliable manufacturer ensures the production and purification of ARHGAP44 protein, maintaining its quality and purity.

      04/13/2021

        the manufacturer's technical support is instrumental in assisting researchers throughout their trials.

        01/05/2020

          Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using ARHGAP44 protein.

          09/10/2019

            The manufacturer's team of experts possesses a deep understanding of the ARHGAP44 protein and its associated protocols.

            07/28/2018

              They can provide valuable guidance in experimental design, optimization, and troubleshooting, helping researchers overcome challenges and maximize the efficiency of their trials.

              07/04/2018

                In conclusion, using ARHGAP44 protein in trials offers distinct advantages for researchers studying cell cycle regulation.

                10/22/2016

                  Manufacturers should provide detailed information about the production process, quality control measures, and purity assessment methods employed.

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