ARHGAP44
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Official Full Name
Rho GTPase activating protein 44
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Synonyms
ARHGAP44; Rho GTPase activating protein 44; rho GTPase-activating protein 44; KIAA0672; RICH 2; RICH2; RICH-2; rho GTPase-activating protein RICH2; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2; NPC-A-10;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ARHGAP44-1278H | Recombinant Human ARHGAP44 | Mammalian Cell | His | ||
Human | ARHGAP44-771H | Recombinant Human ARHGAP44 protein, GST-tagged | Wheat Germ | GST | ||
Human | ARHGAP44-2494H-B | Recombinant Human ARHGAP44 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | ARHGAP44-1090HF | Recombinant Full Length Human ARHGAP44 Protein, GST-tagged | In Vitro Cell Free System | GST | 818 amino acids | |
Human | ARHGAP44-2494H | Recombinant Human ARHGAP44 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ARHGAP44-1878M | Recombinant Mouse ARHGAP44 Protein | Mammalian Cell | His | ||
Mouse | ARHGAP44-685M | Recombinant Mouse ARHGAP44 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | ARHGAP44-685M-B | Recombinant Mouse ARHGAP44 Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
ARHGAP44 involved in several pathways and played different roles in them. We selected most pathways ARHGAP44 participated on our site, such as Rho GTPase cycle, Signal Transduction, Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP44 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Rho GTPase cycle | ARHGAP11A;ARAP2;ARHGAP33;ARHGAP32;TAGAPA;ARHGAP1;GMIP;FAM13B;RHOT1B |
Signal Transduction | C;ADH8B;TTC21B;GPR37L1;IGF2BP1;FGD4A;TNKS2;CSHL1;CRABP1 |
Signaling by Rho GTPases | TAGAP1;RHOT2;NOXO1;RHOT1;IQGAP3;RHPN1;PRC1;MKL1B;RHOF |
ARHGAP44 has several biochemical functions, for example, GTPase activator activity, phospholipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP44 itself. We selected most functions ARHGAP44 had, and list some proteins which have the same functions with ARHGAP44. You can find most of the proteins on our site.
Function | Related Protein |
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GTPase activator activity | ARHGAP23;TBC1D10B;RGS21;ASAP1A;ARHGAP17;ARHGAP42;RASA1;ARHGAP20;ADAP2 |
phospholipid binding | SYTL4;SPTB;NBEAA;ANXA1;OSBPL1A;ANXA9;PICALMA;NBEAL2;DAPP1 |
protein binding | PDP1;NFKB1;UNC119B;CBY1;AAAS;RAB11FIP2;LIMA1;UCHL1;TBKBP1 |
ARHGAP44 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP44 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP44.
HN1
- Q&As
- Reviews
Q&As (8)
Ask a questionCurrently, there are no established animal models specifically targeting ARHGAP44. Creating animal models, such as transgenic or knockout mice, can provide valuable insights into the biological role of ARHGAP44 and its potential implications in various physiological processes or diseases.
The known interacting partners of ARHGAP44 have not been extensively characterized. Large-scale protein interaction studies or specific experimental assays may be required to identify and validate potential binding partners or downstream effectors of ARHGAP44.
As of now, there is no known association between mutations or genetic variants in ARHGAP44 and specific diseases or disorders. This field of research is still in its early stages, and further studies are needed to explore potential links between ARHGAP44 and human pathologies.
The tissue-specific expression pattern of ARHGAP44 has not been extensively investigated. However, publicly available gene expression databases can provide limited information on its expression levels across different tissues and cell types. Further research using techniques such as quantitative PCR or immunohistochemistry can provide more accurate and detailed information on its tissue-specific expression.
The precise implications of ARHGAP44 dysfunction are currently unknown due to limited research on this protein. However, given its potential involvement in regulating cytoskeletal dynamics and cell migration, dysfunctional ARHGAP44 may potentially contribute to abnormalities in these processes, leading to developmental disorders or diseases characterized by aberrant cell motility. Further studies are necessary to unravel its functional consequences.
At present, no specific signaling pathways have been identified in which ARHGAP44 is known to be involved. Further research is essential to explore its potential interactions with other proteins or components of signaling cascades.
ARHGAP44 contains a conserved RhoGAP domain, which is commonly found in GAP proteins and is responsible for catalyzing the hydrolysis of GTP bound to Rho GTPases. This domain suggests that ARHGAP44 may specifically target and inactivate Rho GTPases.
The regulation of ARHGAP44 expression and activity remains poorly understood. More studies are required to investigate the mechanisms that control its expression, potential post-translational modifications, or any regulatory factors that may impact its activity.
Customer Reviews (8)
Write a reviewARHGAP44 protein is an enzyme involved in the digestion of carbohydrates, specifically starch.
A reliable manufacturer ensures the production and purification of ARHGAP44 protein, maintaining its quality and purity.
the manufacturer's technical support is instrumental in assisting researchers throughout their trials.
Manufacturers can actively seek collaborations and partnerships with researchers to develop new applications or optimize methodologies using ARHGAP44 protein.
The manufacturer's team of experts possesses a deep understanding of the ARHGAP44 protein and its associated protocols.
They can provide valuable guidance in experimental design, optimization, and troubleshooting, helping researchers overcome challenges and maximize the efficiency of their trials.
In conclusion, using ARHGAP44 protein in trials offers distinct advantages for researchers studying cell cycle regulation.
Manufacturers should provide detailed information about the production process, quality control measures, and purity assessment methods employed.
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