|Official Full Name||ADP-ribosylation factor-like 13B|
|Background||This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.|
|Synonyms||ARL13B; ADP-ribosylation factor-like 13B; ADP ribosylation factor like 2 like 1 , ARL2L1; ADP-ribosylation factor-like protein 13B; DKFZp761H079; JBTS8; ADP ribosylation factor like 13B; ADP ribosylation factor like 2 like 1; ARL2L1; ARL2-like protein 1; ADP-ribosylation factor-like 2-like 1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ARL13B involved in several pathways and played different roles in them. We selected most pathways ARL13B participated on our site, such as ARL13B-mediated ciliary trafficking of INPP5E, Assembly of the primary cilium, Cargo trafficking to the periciliary membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL13B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|ARL13B-mediated ciliary trafficking of INPP5E||ARL13B|
|Assembly of the primary cilium||PCM1; CKAP5; MAPRE1; RPGRIP1L; MKS1; CC2D2A; BBS9; EXOC1; KIF3A; BBS7|
|Cargo trafficking to the periciliary membrane||ARF4; ARL13B; CCT2; ARL3; EXOC8; MKKS; ARF4A; BBS9; BBS5; SSTR3|
|Organelle biogenesis and maintenance||FLR; MRPS22; CCDC41; MRPS34; IFT74; IFT122; MRPS25; KIF3CB; MRPL46; DYNLRB1|
ARL13B has several biochemical functions, for example, GTP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL13B itself. We selected most functions ARL13B had, and list some proteins which have the same functions with ARL13B. You can find most of the proteins on our site.
|GTP binding||RND2; NPR2; RAB36; TUBA8L2; PIGC; RHOV; MXC; RAB25B; RNGTT; GUCY2C|
|protein binding||SERTAD1; CD2BP2; TMEM171; COMT; XRCC3; AGO3; TREML1; RPS26; HRAS; ARL8A|
ARL13B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL13B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL13B.