ATP2B4 Protein, ATPase, Ca++ transporting, plasma membrane 4


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Official Full Name ATPase, Ca++ transporting, plasma membrane 4
Background Plasma membrane calcium-transporting ATPase 4 is an enzyme that in humans is encoded by the ATP2B4 gene.
Synonyms ATP2B4; ATPase, Ca++ transporting, plasma membrane 4; plasma membrane calcium-transporting ATPase 4; AT2B4_HUMAN; ATP2B2; ATPase Ca++ transporting plasma membrane 4; Cation transporting ATPase; DKFZp686G08106; DKFZp686M088; Matrix remodelling associated 1; Matrix remodelling associated protein 1; Matrix-remodeling-associated protein 1; MXRA 1; MXRA1; OTTHUMP00000034088; OTTHUMP00000034089; Plasma membrane calcium ATPase 4; Plasma membrane calcium ATPase isoform 4; Plasma membrane calcium pump isoform 4; Plasma membrane calcium transporting ATPase 4; PMCA 4; PMCA4; PMCA4b; PMCA4x; Sarcolemmal calcium pump; ATPase, Ca++ transporting, plasma membrane 4 ATP synthase, H+ transporting, mitochondrial F1
    • Species :
    • Human
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP2B4-27795TH Recombinant Human ATP2B4 Wheat Germ N/A
    Human ATP2B4-2945H Recombinant Human ATP2B4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ATP2B4-973H Recombinant Human ATP2B4 protein, GST-tagged Wheat Germ GST
    Rat ATP2B4-864R Recombinant Rat ATP2B4 Protein Mammalian Cell His
    Rhesus Macaque ATP2B4-451R Recombinant Rhesus monkey ATP2B4 Protein, His-tagged Mammalian Cell His
    Zebrafish ATP2B4-4741Z Recombinant Zebrafish ATP2B4 Mammalian Cell His

    ATP2B4 involved in several pathways and played different roles in them. We selected most pathways ATP2B4 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2B4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway DRD1; ATP2A2B; HTR5AL; CALM1B; HTR2C; ADRA1D; VDAC3; GRIN2D; CAMK4; NOS1
    cGMP-PKG signaling pathway PLCB3; ITPR1; NPPB; ATP1B2; FXYD2; MEF2D; CALM1; SLC25A31; PLN; AGTR1B
    cAMP signaling pathway PTCH1; RAC1; PDE3A; PDE3B; PLCE1; PIK3CG; GHSR; PRKACA; CREB3L2; RAC2
    Adrenergic signaling in cardiomyocytes ATP1B4; ACTC1B; TNNI3; MAPK13; CREB3L3; CACNA1D; CACNG1; ATF4B1; GNA15.1; CALM1
    Salivary secretion VAMP2; NOS1; ITPR3; PLCB2; ATP2B4; CD38; ATP1B1; PLCB1; GUCY1B3; PRKCG
    Pancreatic secretion ATP2A1; PRKCB; PLCB4; KCNMA1; PLA2G10; CTRL; Cel; PRKCG; PLA2G12B; PLA2G2E

    ATP2B4 has several biochemical functions, for example, ATP binding, PDZ domain binding, calcium-transporting ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2B4 itself. We selected most functions ATP2B4 had, and list some proteins which have the same functions with ATP2B4. You can find most of the proteins on our site.

    Function Related Protein
    PDZ domain binding PTENA; CADM1; FZD2; LRP2; LNX1; FZD7; PROSAPIP1; EXOC4; FZD8; SLC9A3R2
    calcium-transporting ATPase activity ATP2A1; ATP2B1A; ATP2C2; ATP2A2; ATP2A1L; ATP2B2; ATP2B3A; ATP2A2A; ATP2B3B; ATP2A3
    calmodulin binding MYO1C; SPTBN1; MARCKSL1A; ORAI1; SPATA17; MYO9B; PLA2G6; CALD1B; CAMSAP1; ADCY1
    metal ion binding AARS; ZNF582; HPD; ZFP579; PRKAA2; ADNP2; THAP5; GALNT6; ZBTB43; BCL6A
    nitric-oxide synthase binding NOS1AP; CALM1; CAV1; ATP2B4; ACTB; SLC6A4; DNM3; CALM3; SLC14A2; CAV3
    nitric-oxide synthase inhibitor activity ATP2B4
    contributes_to nitric-oxide synthase inhibitor activity ATP2B4
    protein binding C4BPB; ZMYM2; UCP2; SERP1; ANKFY1; CCDC130; WDR12; RIPK3; TMEM149; KIF20A
    protein phosphatase 2B binding AKAP1; SLC9A1; SOD1; BAD; MYOZ2; AKAP5; ATP2B4; PPP3CB
    scaffold protein binding ATP2B4; NLGN4Y; PARK7; NLGN1; SHANK1; CASP8; SHANK3; SCN5A; KRT5; KRT15
    contributes_to sodium channel regulator activity ATP2B4; SNTA1

    ATP2B4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2B4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2B4.

    Nos1; CALCA; STIM1; Nos1; 15-deoxy-delta(12,14; EGFR; 1C; CDK7; YWHAE

    Brandenburger, T; Strehler, EE; et al. Switch of PMCA4 Splice Variants in Bovine Epididymis Results in Altered Isoform Expression during Functional Sperm Maturation. JOURNAL OF BIOLOGICAL CHEMISTRY 286:7938-7946(2011).
    Mangialavori, I; Giraldo, AMV; et al. A New Conformation in Sarcoplasmic Reticulum Calcium Pump and Plasma Membrane Ca2+ Pumps Revealed by a Photoactivatable Phospholipidic Probe. JOURNAL OF BIOLOGICAL CHEMISTRY 284:4823-4828(2009).

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