|Official Full Name||ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2|
|Background||This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene.|
|Synonyms||ATP6V1G2; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2; ATP6G, ATP6G2, ATPase, H+ transporting, lysosomal (vacuolar proton pump) , ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 2; V-type proton ATPase subunit G 2; Em:AC004181.3; NG38; Vma10; ATP6G; ATP6G2; ATPase H+ transporting lysosomal (vacuolar proton pump) subunit G; ATPase H+ transporting lysosomal 13kDa V1 subunit G2; H(+) transporting two sector ATPase subunit G2; NG 38; OTTHUMP00000036058; OTTHUMP00000036060; V ATPase 13 kDa subunit 2; V ATPase G subunit 2; V ATPase subunit G 2; Vacuolar ATP synthase subunit G 2; Vacuolar proton pump G subunit 2; Vacuolar proton pump subunit G 2; VMA 10; OTTHUMP00000029286; OTTHUMP00000165896; OTTHUMP00000215151; V-ATPase 13 kDa subunit 2; H(+)-transporting two-sector ATPase, subunit G2; ATPase, H+ transporting,|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ATP6V1G2 involved in several pathways and played different roles in them. We selected most pathways ATP6V1G2 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6V1G2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Oxidative phosphorylation||ATP6V0A1A; NDUFB7; NDUFA4; UQCR11; NDUFS1; SDHDB; ATP6V0A2B; ATPV0E2; COX4I2; UQCRC2|
|Metabolic pathways||NDUFV3; B3GNT5; ST8SIA1; ACADM; ACSM4; GALNT6; C1GALT1B; IDUA; HADHB; CYP2C37|
|Phagosome||ATP6V0A1; HLA-DPB1; ABCB3L1; ATP6V0E; TLR2; TUBA3B; CTSLA; TUBA4A; RILP; ITGAM|
|Synaptic vesicle cycle||ATP6V1G1; NAPA; ATP6V0D1; DNM3; NSF; ATP6V1B1; ATP6V1E2; SLC17A6; RIMS1; STX3|
|Collecting duct acid secretion||ATP6V1E1; Car2; ATP6V1G3; ATP6V1D; ATP6V1G2; ATP4B; CLCNKB; ATP6V0D2; ATP6V0E1; ATP6V1A|
|Vibrio cholerae infection||ATP6V0A2; ATP6V0A4; KDELR1; MUC2; PDIA4; PLCG2; ATP6AP1; ATP6V0B; ATP6V0D1; ERO1L|
|Epithelial cell signaling in Helicobacter pylori infection||ATP6V1G3; ATP6V0A2; ATP6V1G1; LYN; NFKBIA; F11R; PLCG2; TCIRG1; ATP6V1E1; ATP6V1D|
|Rheumatoid arthritis||Ctsl; LTB; TNFSF11; ATP6V0D2; ATP6V1D; IL6; CCL5; ATP6V0B; HLA-DRA; CCL3|
ATP6V1G2 has several biochemical functions, for example, hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6V1G2 itself. We selected most functions ATP6V1G2 had, and list some proteins which have the same functions with ATP6V1G2. You can find most of the proteins on our site.
|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances||ATP6V1BA; ATP6V1B1; ATP6V1AA; ATP6V1G2|
ATP6V1G2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6V1G2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6V1G2.
ATP6V1E1; GABARAPL2; IQCB1