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Asic2

Official Full Name

acid-sensing (proton-gated) ion channel 2

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Rhesus Macaque
Zebrafish

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
MYC
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	ASIC2-9103HCL	Recombinant Human ACCN1 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	Asic2-508M	Recombinant Mouse Asic2 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK	Inquiry
Rat	ASIC2-822R	Recombinant Rat ASIC2 Protein	Mammalian Cell	His	Inquiry
Rat	ASIC2-478R	Recombinant Rat ASIC2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	ASIC2-478R-B	Recombinant Rat ASIC2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	ASIC2-427R	Recombinant Rhesus monkey ASIC2 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	ASIC2-256R-B	Recombinant Rhesus Macaque ASIC2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	ASIC2-256R	Recombinant Rhesus Macaque ASIC2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Zebrafish	ASIC2-12803Z	Recombinant Zebrafish ASIC2	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Asic2 Related Articles

Asic2 involved in several pathways and played different roles in them. We selected most pathways Asic2 participated on our site, such as Taste transduction, Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with Asic2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Taste transduction	TAS2R108;PDE1A;TAS1R3;TAS2R38;GRM4;Adcy4;TAS2R104;TAS2R139;TAS2R129
Inflammatory mediator regulation of TRP channels	CYP4A10;CYP4A12A;PLA2G4F;CALML3;BDKRB1;IL1R1;TRPM8;PLA2G4C;PIK3R3

Asic2 has several biochemical functions, for example, ligand-gated sodium channel activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Asic2 itself. We selected most functions Asic2 had, and list some proteins which have the same functions with Asic2. You can find most of the proteins on our site.

Function	Related Protein
ligand-gated sodium channel activity	ASIC1A;ACCN5;ASIC1C;ASIC3;ASIC1;ASIC1B;ASIC4A;ACCN3;ASIC5
protein binding	RRAS2;RIPK1L;ATF4;NDP;UBA52;SULT2A1;TPP1;CHN1;FBXO2

Asic2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Asic2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Asic2.

PICK1; Pick1

Cabo, R; Alonso, P; et al. ASIC2 is present in human mechanosensory neurons of the dorsal root ganglia and in mechanoreceptors of the glabrous skin. HISTOCHEMISTRY AND CELL BIOLOGY 143:267-276(2015).

Gannon, KP; Mckey, SE; et al. Altered myogenic vasoconstriction and regulation of whole kidney blood flow in the ASIC2 knockout mouse. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 308:F339-F348(2015).