bcl2l14
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  • Official Full Name
  • BCL2-like 14 (apoptosis facilitator)
  • Background
  • The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene.
  • Synonyms
  • BCL2L14; BCL2-like 14 (apoptosis facilitator); apoptosis facilitator Bcl-2-like protein 14; BCL G; BCLG; bcl2-L-14; apoptosis regulator BCL-G
Cat.#:BCL2L14-10182HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BCL2L14, His-tagged
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Cat.#:BCL2L14-155HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BCL2L14 Protein, GST-tagged
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Cat.#:BCL2L14-2347MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BCL2L14 Protein
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Cat.#:BCL2L14-961RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BCL2L14 Protein
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Cat.#:BCL2L14-8484HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BCL2L14 293 Cell Lysate
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Involved Pathway

BCL2L14 involved in several pathways and played different roles in them. We selected most pathways BCL2L14 participated on our site, such as Direct p53 effectors, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL2L14 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Direct p53 effectors
DDB2; CSE1L; CTSD; HIC1; NDRG1; EDN2; FDXR; SCN3B; CCNK; S100A2

Protein Function

BCL2L14 has several biochemical functions, for example, protein binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL2L14 itself. We selected most functions BCL2L14 had, and list some proteins which have the same functions with BCL2L14. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein APIP; NPRL2; SNRPE; PKIA; EXOSC5; NCALD; MUL1; HESX1; PIGK; SELE
Function protein kinase binding
Related Protein PRKAG2; C10orf46; CEP68; DNM2; RHOD; NCS1; CCNT2A; PRKRIP1; ZC3HC1; PRKAB1

Interacting Protein

BCL2L14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL2L14 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL2L14.
MELK

BCL2L14 Related Articles

Feurstein, S; Rucker, FG; et al. Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype. BMC GENOMICS 15:-(2014).
Zhang, S; Feng, XL; et al. Genome-wide analysis of DNA methylation in tongue squamous cell carcinoma. ONCOLOGY REPORTS 29:1819-1826(2013).

BCL2L14 Related Gene Family

BCL2 Gene Family