BCL2L14 Protein, BCL2-like 14 (apoptosis facilitator)

BCL2L14

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BCL2L14

Official Full Name BCL2-like 14 (apoptosis facilitator)
Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene.
Synonyms BCL2L14; BCL2-like 14 (apoptosis facilitator); apoptosis facilitator Bcl-2-like protein 14; BCL G; BCLG; bcl2-L-14; apoptosis regulator BCL-G
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BCL2L14-10182H Recombinant Human BCL2L14, His-tagged E.coli His
    Human BCL2L14-155H Recombinant Human BCL2L14 Protein, GST-tagged Wheat Germ GST
    Human BCL2L14-8484HCL Recombinant Human BCL2L14 293 Cell Lysate HEK293 N/A
    Mouse BCL2L14-2347M Recombinant Mouse BCL2L14 Protein Mammalian Cell His
    Rat BCL2L14-961R Recombinant Rat BCL2L14 Protein Mammalian Cell His

    BCL2L14 involved in several pathways and played different roles in them. We selected most pathways BCL2L14 participated on our site, such as Direct p53 effectors, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL2L14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Direct p53 effectors EPHA2; S100A2; GADD45A; PRDM1; AIFM2; DDX5; DDB2; CCNK; CEBPZ; DGCR8

    BCL2L14 has several biochemical functions, for example, protein binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL2L14 itself. We selected most functions BCL2L14 had, and list some proteins which have the same functions with BCL2L14. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SDPR; PAEP; RNF149; MT2A; KLK8; MPLKIP; CCDC106; RALBP1; DNTT; FKBP1A
    protein kinase binding CCNB1; TP53; CDC25C; RB1CC1; RAB8A; GOLGA2; EPHA1; GCSAM; SQSTM1; IRS2

    BCL2L14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL2L14 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL2L14.

    MELK

    Feurstein, S; Rucker, FG; et al. Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype. BMC GENOMICS 15:-(2014).
    Zhang, S; Feng, XL; et al. Genome-wide analysis of DNA methylation in tongue squamous cell carcinoma. ONCOLOGY REPORTS 29:1819-1826(2013).

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