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BCL3

  • Official Full Name

    B-cell CLL/lymphoma 3

  • Overview

    The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
  • Synonyms

    BCL4; D19S37; BCL3; B-cell lymphoma 3 protein; BCL-3; OTTHUMP00000200151; OTTHUMP00000200152; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; chronic lymphatic leukemia protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BCL3-157H Recombinant Human BCL3 Protein, GST-tagged Wheat Germ GST
Human BCL3-151H Recombinant Human BCL3 Mammalian Cell His
Human BCL3-8481HCL Recombinant Human BCL3 293 Cell Lysate HEK293 N/A
Human BCL3-1724H Recombinant Human BCL3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human BCL3-1606HF Recombinant Full Length Human BCL3 Protein, GST-tagged In Vitro Cell Free System GST 446 amino acids
Human BCL3-2538H-B Recombinant Human BCL3 Protein Pre-coupled Magnetic Beads HEK293
Human BCL3-2538H Recombinant Human BCL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BCL3-2350M Recombinant Mouse BCL3 Protein Mammalian Cell His
Mouse Bcl3-1859M Recombinant Mouse Bcl3 protein, His & T7-tagged E.coli His/T7 Pro82~Leu341 (Accession # Q9Z2F6)
Mouse BCL3-995M Recombinant Mouse BCL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse BCL3-995M-B Recombinant Mouse BCL3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Bcl3-700M Recombinant Mouse Bcl3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Bcl3-1860R Recombinant Rat Bcl3 protein, His & T7-tagged E.coli His/T7 Asp127~Asn376 (Accession # D3ZQF8)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • BCL3 Related Articles
  • BCL3 Related Gene Family

BCL3 involved in several pathways and played different roles in them. We selected most pathways BCL3 participated on our site, such as TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
TNF signaling pathwayCXCL3;TNFRSF1B;MMP9;SOCS3;VEGFC;PIK3CA;VCAM1;IL18R1;TNFAIP3

BCL3 has several biochemical functions, for example, DNA binding, protein binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL3 itself. We selected most functions BCL3 had, and list some proteins which have the same functions with BCL3. You can find most of the proteins on our site.

Function Related Protein
DNA bindingPOLDIP2;HMGA2;ENO1;UBN1;NR4A1;DEAF1;ETV5B;JUNB;ASCL4
protein bindingFKBP1A;TMUB2;GABARAP;DYRK1B;TH1L;OSGIN1;LDLR;PPP2R4;CSRNP2
protein binding, bridgingTCAP;COL8A2;RBM14;FSCN1;FLRT3;FSCN3;FBXW7;ST13;NEFH
transcription factor activity, sequence-specific DNA bindingTRPS1;OTX1A;AHRRB;ZSCAN23;NR1D2A;DBPA;RELB;SPZ1;ZSCAN20
transcription factor bindingNAB1;THRA;HDAC8;ATOH8;HMGA2;NAB2;CSNK2B;TNFRSF10A;FHL2

BCL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL3.

LCK; BCL10; CTBP2; PIR; FYN; ANKRD28; NFKB1; NFKB2; RELB; RELA; REL

Komai, K; Niwa, Y; et al. Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. FEBS LETTERS 589:738-743(2015).
Chen, H; Zhang, Q; et al. Patterning of light-extraction nanostructures on sapphire substrates using nanoimprint and ICP etching with different masking materials. NANOTECHNOLOGY 26:-(2015).
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