bcl3
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  • Official Full Name
  • B-cell CLL/lymphoma 3
  • Background
  • The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
  • Synonyms
  • BCL4; D19S37; BCL3; B-cell lymphoma 3 protein; BCL-3; OTTHUMP00000200151; OTTHUMP00000200152; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; chronic lymphatic leukemia protein
Cat.#:BCL3-151HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human BCL3
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Cat.#:BCL3-157HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human BCL3 Protein, GST-tagged
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Cat.#:Bcl3-1859MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Bcl3 protein, His & T7-tagged
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Cat.#:BCL3-2350MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BCL3 Protein
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Cat.#:Bcl3-1860RTag:His|T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Bcl3 protein, His & T7-tagged
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Cat.#:BCL3-8481HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human BCL3 293 Cell Lysate
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Involved Pathway

BCL3 involved in several pathways and played different roles in them. We selected most pathways BCL3 participated on our site, such as TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with BCL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
TNF signaling pathway
CFLAR; RIPK1; MAGI2; PIK3R5; CXCL1; ATF4; CXCL2; MLKL; CXCL5; MAPK3

Protein Function

BCL3 has several biochemical functions, for example, DNA binding, protein binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by BCL3 itself. We selected most functions BCL3 had, and list some proteins which have the same functions with BCL3. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein EMX1; PIAS1; SOX21; SCXB; KAT6B; EGR1; KLF5; MYBL2B; POLD1; IRX3A
Function protein binding
Related Protein PER2; RNF7; FAIM; IMMT; ABCD1; MZT1; PRKACA; C10orf33; MRPL20; PCNP
Function protein binding, bridging
Related Protein SYNM; TJP2; MEN1; EVPL; CAV2; NMD3; COL1A2; CBX5; FLRT2; PPP2R3A
Function transcription factor activity, sequence-specific DNA binding
Related Protein MSRB2; HEY2; NEUROG1; GBX2; NFIX; ELF1; ZNF821; T; GTF2H4; UBN2
Function transcription factor binding
Related Protein CHCHD2; INSIG2; BCL2; STK4; NFYC; HAND1; NAB1; APBB1; PIAS1; SMARCD3

Interacting Protein

BCL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BCL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of BCL3.
LCK; BCL10; CTBP2; PIR; FYN; ANKRD28; NFKB1; NFKB2; RELB; RELA; REL

BCL3 Related Articles

Komai, K; Niwa, Y; et al. Pirin regulates epithelial to mesenchymal transition independently of Bcl3-Slug signaling. FEBS LETTERS 589:738-743(2015).
Chen, H; Zhang, Q; et al. Patterning of light-extraction nanostructures on sapphire substrates using nanoimprint and ICP etching with different masking materials. NANOTECHNOLOGY 26:-(2015).

BCL3 Related Gene Family

BCL2 Gene Family