Recombinant Human BCL3 Protein, GST-tagged

• Cat.No.: BCL3-157H
• Product Overview: Human BCL3 full-length ORF ( NP_005169.1, 1 a.a. - 446 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 73.2 kDa
• AA Sequence: MDEGPVDLRTRPKAAGLPGAALPLR KRPLRAPSPEPAAPRGAAGLVVPLD PLRGGCDLPAVPGPPHGLARPEALY YPGALLPLYPTRAMGSPFPLVNLPT PLYPMMCPMEHPLSADIAMATRADE DGDTPLHIAVVQGNLPAVHRLVNLF QQGGRELDIYNNLRQTPLHLAVITT LPSVVRLLVTAGASPMALDRHGQTA AHLACEHRSPTCLRALLDSAAPGTL DLEARNYDGLTALHVAVNTECQETV QLLLERGADIDAVDIKSGRSPLIHA VENNSLSMVQLLLQHGANVNAQMYS GSSALHSASGRGLLPLVRTLVRSGA DSSLKNCHNDTPLMVARSRRVIDIL RGKATRPASTSQPDPSPDRSANTSP ESSSRLSSNGLLSASPSSSPSQSPP RDPPGFPMAPPNFFLPSPSPPAFLP FAGVLRGPGRPVPPSPAPGGS
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: BCL3 B-cell CLL/lymphoma 3 [ Homo sapiens ]
• Official Symbol: BCL3
• Synonyms: BCL3; B-cell CLL/lymphoma 3; BCL4, D19S37; B-cell lymphoma 3 protein; B cell leukemia/lymphoma 3; B cell lymphoma 3 encoded protein; chronic lymphatic leukemia protein; BCL-3; proto-oncogene BCL3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3-encoded protein; BCL4; D19S37
• Gene ID: 602
• mRNA Refseq: NM_005178
• Protein Refseq: NP_005169
• MIM: 109560
• UniProt ID: P20749