Bscl2 Protein, Berardinelli-Seip congenital lipodystrophy 2 (seipin)


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Official Full Name Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Background This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms BSCL2; Berardinelli-Seip congenital lipodystrophy 2 (seipin); GNG3LG, spastic paraplegia 17 (Silver syndrome) , SPG17; seipin; Bernardinelli-Seip congenital lipodystrophy type 2 protein; HMN5; SPG17; GNG3LG; MGC4694; FLJ16651
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Bscl2-1035M Recombinant Mouse Bscl2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human BSCL2-357H Recombinant Human BSCL2 Protein, GST-tagged Wheat Germ GST
    Human BSCL2-8402HCL Recombinant Human BSCL2 293 Cell Lysate HEK293 N/A
    Mouse BSCL2-2505M Recombinant Mouse BSCL2 Protein Mammalian Cell His
    Rat BSCL2-1021R Recombinant Rat BSCL2 Protein Mammalian Cell His
    Rhesus Macaque BSCL2-571R Recombinant Rhesus monkey BSCL2 Protein, His-tagged Mammalian Cell His
    Zebrafish BSCL2-3521Z Recombinant Zebrafish BSCL2 Mammalian Cell His

    Bscl2 involved in several pathways and played different roles in them. We selected most pathways Bscl2 participated on our site, such as Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Bscl2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adipogenesis FRZB; DVL1; GATA2; SMAD3B; BMP3; HMGA1; AGPAT2; GATA2A; KLF7; CTNNB1

    Bscl2 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Bscl2 itself. We selected most functions Bscl2 had, and list some proteins which have the same functions with Bscl2. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function GPM6B; SMIM1; C14orf2; WDR74; JAGN1B; ACSM3; PLEKHM3; CUX1B; OLFML3B; SLC25A48
    protein binding TAF8; NEU4; ZNF436; MIEF1; SORBS2; RBM22; SMAP2; OAS3; ACTL8; TDG

    Bscl2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Bscl2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Bscl2.

    TMEM19; SMIM3; Hoxa1; gabD; USE1

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