c10orf2
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  • Official Full Name
  • chromosome 10 open reading frame 2
  • Synonyms
  • C10ORF2;chromosome 10 open reading frame 2;infantile onset spinocerebellar ataxia (autosomal recessive), IOSCA;twinkle protein, mitochondrial;FLJ21832;PEO;PEO1;twinkle;TWINKLE;TWINL;ataxin 8;mitochondrial twinkle protein;T7-like mitochondrial DNA helicase;progressive external ophthalmoplegia 1 protein;T7 gp4-like protein with intramitochondrial nucleoid localization;SCA8;ATXN8;IOSCA;PEOA3;SANDO;MTDPS7;
Cat.#:C10orf2-8371HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human C10orf2 293 Cell Lysate
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Involved Pathway

C10orf2 involved in several pathways and played different roles in them. We selected most pathways C10orf2 participated on our site, such as Mitochondrial biogenesis, Organelle biogenesis and maintenance, Transcriptional activation of mitochondrial biogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C10orf2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Mitochondrial biogenesis
MTERF; ESRRA; GABPA; TFB1M; TFB2M; POLRMT; PPARGC1B; PPRC1; POLG2; C10orf2
Organelle biogenesis and maintenance
NPHP1; UNC119B; EXOC8; MTIF3; MRPL44; MRPS31; MRPS28; CYS1; BBS10; POLRMT
Transcriptional activation of mitochondrial biogenesis
MTERF; POLG2; C10orf2; POLRMT; PPRC1; GABPB1; GABPA; TFB1M

Protein Function

C10orf2 has several biochemical functions, for example, 5-3 DNA helicase activity, ATP binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C10orf2 itself. We selected most functions C10orf2 had, and list some proteins which have the same functions with C10orf2. You can find most of the proteins on our site.
Function
Related Protein
Function 5-3 DNA helicase activity
Related Protein PEO1; ERCC2; C10orf2; DNA2
Function ATP binding
Related Protein DDX25; KITB; CAMK1DB; NADSYN1; PTK6B; ATP2B2; CCT6A; ADCY6; STK19; PHKG1B
Function protease binding
Related Protein ITGAV; SERPINB6; STIM1; DERL1; Serpina1c; CFLAR; TIMP2; CCBE1; A2M; CD70
Function single-stranded DNA binding
Related Protein TDP1; ERCC1; MCM6; RAD51L1; NABP1; NABP1A; BLM; OBFC2B; HSPD1; PURA

Interacting Protein

C10orf2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C10orf2 here. Most of them are supplied by our site. Hope this information will be useful for your research of C10orf2.
SQSTM1; SUMO2; AKTIP; RAD9A; g3v3g9_human; TPM1; TP53; CLTA; TRIM27; YWHAH; ICT1; CHD9; SPECC1L; PYHIN1; PHLDB2; LYSMD2; ARPC5L; ACTL8; NCOA5; EPB41L5

C10orf2 Related Articles

Muneta, Y; Kikuma, R; et al. Molecular cloning, chromosomal location, and biological activity of porcine interleukin-21. JOURNAL OF VETERINARY MEDICAL SCIENCE 66:269-275(2004).
Xie, JP; Cai, T; et al. The zinc-finger transcription factor INSM1 is expressed during embryo development and interacts with the cbl-associated protein. GENOMICS 80:54-61(2002).