|Official Full Name||C12orf65 chromosome 12 open reading frame 65 [ Homo sapiens (human) ]|
|Background||This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants.|
|Synonyms||C12orf65; chromosome 12 open reading frame 65; CL065_HUMAN; COXPD7; mitochondrial; Probable peptide chain release factor C12orf65; probable peptide chain release factor C12orf65, mitochondrial; SPG55|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
C12orf65 involved in several pathways and played different roles in them. We selected most pathways C12orf65 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with C12orf65 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
C12orf65 has several biochemical functions, for example, aminoacyl-tRNA hydrolase activity, ribosome binding, translation release factor activity, codon nonspecific. Some of the functions are cooperated with other proteins, some of the functions could acted by C12orf65 itself. We selected most functions C12orf65 had, and list some proteins which have the same functions with C12orf65. You can find most of the proteins on our site.
|aminoacyl-tRNA hydrolase activity||PTRHD1; PTRH1; PTRH2; ICT1; C12orf65|
|ribosome binding||EIF5A2; IGHMBP2; EIF2S1B; BAG6; C12orf65; EIF3K; EIF2S1A; ETF1A; PPP1R2P9; RPN2|
|translation release factor activity, codon nonspecific||ICT1; C12orf65|
|NOT translation release factor activity, codon specific||ICT1; C12orf65|
C12orf65 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C12orf65 here. Most of them are supplied by our site. Hope this information will be useful for your research of C12orf65.