|Official Full Name||chromosome 19 open reading frame 2|
|Background||The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.|
|Synonyms||C19ORF2; chromosome 19 open reading frame 2; unconventional prefoldin RPB5 interactor; FLJ10575; NNX3; PPP1R19; protein phosphatase 1; regulatory subunit 19; RMP; RPB5 mediating protein; URI; RNA polymerase II subunit 5 mediating protein; RPB5-mediating protein; protein phosphatase 1, regulatory subunit 19; RNA polymerase II subunit 5-mediating protein; RNA polymerase II, subunit 5-mediating protein|
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C19ORF2 involved in several pathways and played different roles in them. We selected most pathways C19ORF2 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with C19ORF2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
C19ORF2 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by C19ORF2 itself. We selected most functions C19ORF2 had, and list some proteins which have the same functions with C19ORF2. You can find most of the proteins on our site.
C19ORF2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C19ORF2 here. Most of them are supplied by our site. Hope this information will be useful for your research of C19ORF2.