|Official Full Name||complement component 1, q subcomponent, B chain|
|Background||This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in;order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus;erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six;C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The;A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of;human complement subcomponent C1q.|
|Synonyms||C1QB; complement component 1, q subcomponent, B chain; complement component 1, q subcomponent, beta polypeptide; complement C1q subcomponent subunit B; Complement component 1 q subcomponent B chain; Complement component 1 q subcomponent beta polypeptide; Complement component C1q B chain; Complement subcomponent C1q chain B; OTTHUMP00000002940; OTTHUMP00000002941; complement component C1q, B chain|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
C1QB involved in several pathways and played different roles in them. We selected most pathways C1QB participated on our site, such as Complement and coagulation cascades, Prion diseases, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1QB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Complement and coagulation cascades||THBD; C1QB; CD46; F2; MBL2; MBL1; F5; VWF; SERPINA1D; CFH|
|Prion diseases||PRNP; Hc; C6; C8B; PRKACB; PRKACA; HSPA5; C1QB; MAPK1; C7|
|Pertussis||C1S; C1QB; CASP7; GM5077; TICAM2; C4BPB; MAPK9; IL1A; MAPK12; C1QA|
|Chagas disease (American trypanosomiasis)||IL6; CCL2; GNA14; ACE; PIK3CD; CFLAR; IKBKG; PLCB3; PIK3R5; C1QB|
|Staphylococcus aureus infection||HLA-DRB4; C1QC; C3; SELP; FPR1; C2; HLA-DOA; DSG1C; FCGR2B; HLA-DRA|
|Systemic lupus erythematosus||HIST2H4A; HIST1H4E; HIST1H2AN; C1QC; GM14476; TRIM21; HLA-DRA; HIST2H3A; H2-AA; HIST1H4N|
C1QB has several biochemical functions, for example, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by C1QB itself. We selected most functions C1QB had, and list some proteins which have the same functions with C1QB. You can find most of the proteins on our site.
|protein binding||MRAP; JAM2A; SP2; CHGB; ZBTB16; SPEF2; NDUFAF4; COASY; TMEM19; GATAD2A|
|protein homodimerization activity||SDCBP2; ARID3A; AXIN1; NETO2; GYS2; ACTN4; ACOT7; MBL1; GDF6; PDK2|
C1QB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QB here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QB.
C1QA; RELA; q7chk1_yerpe; sbcD; treC; q81sh2_bacan; EDA2R