C22orf28
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Official Full Name
chromosome 22 open reading frame 28 -
Synonyms
C22ORF28;chromosome 22 open reading frame 28;26935;ENSG00000100220;FAAP;HSPC117;DJ149A16.6;RP1-149A16.6;22q12;tRNA-splicing ligase RtcB homolog;tRNA-splicing ligase RtcB homolog;ankyrin repeat domain 54;focal adhesion-associated protein;EC 6.5.1.3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| C22orf28-8093HCL | Recombinant Human C22orf28 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
C22orf28 involved in several pathways and played different roles in them. We selected most pathways C22orf28 participated on our site, such as Gene Expression,tRNA processing,tRNA processing in the nucleus, which may be useful for your reference. Also, other proteins which involved in the same pathway with C22orf28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gene Expression | AIMP2,ZNF124,TSEN2,KIAA1456,EIF2C3,SEC61B,HNRNPA0,TXNL4A,TSEN34,ZNF689 |
| tRNA processing in the nucleus | RPP14,TSEN54,RPP30,ELAC2,RPP38,FAM98B,C14orf166,XPOT,TSEN15,ZBTB8OS |
| tRNA processing | TRMT12,POP7,MANEA,RPP30,POP1,TRMT44,RPP14,TRDMT1,PUS1,TYW3 |
Protein Function
C22orf28 has several biochemical functions, for example, ATP binding,RNA ligase (ATP) activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C22orf28 itself. We selected most functions C22orf28 had, and list some proteins which have the same functions with C22orf28. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | KRTAP10-5,POU4F1,TYR,RGR,C7orf59,TAF7,MYB,FGFBP1,CDC25C,SEMG1 |
| vinculin binding | TLN1,DAG1,DMD,SORBS3,ACTN1,SYNM,NRAP,CTNNA1,PXN |
| RNA ligase (ATP) activity | RTCB |
| ATP binding | SPO11,GSK3AB,ABCC12,NLRP4B,MCM5,HSPA8,EPHA5,UBE2W,KCNJ8,DQX1 |
| poly(A) RNA binding | LRRC47,PPIL4,MATR3,RTCD1,MSI2,SART3,EIF2C3,MRPL32,SNRPD3,HIST1H4F |
| metal ion binding | AGFG1A,CLIP1,RFESD,YY1B,ZFP428,TP63,LOXL2B,RTCB,ZFP629,ZBTB3 |
Interacting Protein
C22orf28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C22orf28 here. Most of them are supplied by our site. Hope this information will be useful for your research of C22orf28.
APPL1;CRK;YWHAZ;TRMT10C;NS1;8-aha-camp;8-aha-omethyladenosine;ere_dna
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References
- Remus, BS; Shuman, S; et al. Distinctive kinetics and substrate specificities of plant and fungal tRNA ligases. RNA-A PUBLICATION OF THE RNA SOCIETY 20:462-473(2014).
- Huang, SYN; Pommier, Y; et al. Cross-over of RNA 3'-phosphate ligase into the DNA world. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:20354-20355(2013).
