|Official Full Name||chromosome 7 open reading frame 11|
|Background||The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.|
|Synonyms||C7ORF11; chromosome 7 open reading frame 11; TTD non-photosensitive 1 protein; non photosensitive 1; ORF20; tricothiodystrophy; TTDN1; ABHS; TTD nonphotosensitive 1 protein; Russell-Silver syndrome region|
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C7ORF11 involved in several pathways and played different roles in them. We selected most pathways C7ORF11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with C7ORF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
C7ORF11 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C7ORF11 itself. We selected most functions C7ORF11 had, and list some proteins which have the same functions with C7ORF11. You can find most of the proteins on our site.
C7ORF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C7ORF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of C7ORF11.