|Official Full Name||Cancer Antigen 72-4|
|Background||Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including breast, colon, and pancreaticcells. It is a mucin-like molecule with a molar mass of over 1000 kDa. TAG-72 is a a tumor marker and can be measured with radioimmunoassays like CA 72-4, which uses indium (111In) satumomab pendetide and iodine (125I) CC49monoclonal antibody. This assay has a good specificity for gastric cancer, with a correlation to the neoplasia's extension. It is used to identify relapses of the disease and to follow up the treatment. TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.|
|Synonyms||TAG 72; Tumor associated Glycoprotein 72; TAG72|
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CA 72-4 involved in several pathways and played different roles in them. We selected most pathways CA 72-4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CA 72-4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
CA 72-4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CA 72-4 itself. We selected most functions CA 72-4 had, and list some proteins which have the same functions with CA 72-4. You can find most of the proteins on our site.
CA 72-4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA 72-4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA 72-4.