CACNG8
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Official Full Name
calcium channel, voltage-dependent, gamma subunit 8
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Synonyms
CACNG8; calcium channel, voltage-dependent, gamma subunit 8; voltage-dependent calcium channel gamma-8 subunit; TARP gamma-8; transmembrane AMPAR regulatory protein gamma-8; neuronal voltage-gated calcium channel gamma-8 subunit; FLJ16240; FLJ30598;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- Involved Pathway
- Protein Function
- Interacting Protein
CACNG8 involved in several pathways and played different roles in them. We selected most pathways CACNG8 participated on our site, such as MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with CACNG8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | ACVR1C;RPS6KAL;JIP1;AKT3A;CACNB4A;CACNA2D4;MAPK12;HSPA1L;MAPK10 |
| Cardiac muscle contraction | TNNC1A;MYL2;COX7C;MYH15;CACNG2;TMEM8C;COX6A2;ATP1B1B;UQCRQ |
| Adrenergic signaling in cardiomyocytes | ATP1B1;RAPGEF4;ADRB2B;ATP2B2;ATF4;BCL2A;ACTC1;TNNT2;CREB1A |
| Oxytocin signaling pathway | NOS3;PLCB3;PPP3R2;PIK3R3;PPP1R12C;NFATC2;GUCY1B3;MAP2K1;CALML3 |
| Hypertrophic cardiomyopathy (HCM) | ACTB;TNNC1;TNF;LMNA;ACE;ITGA2B;DMD;ITGA9;TGFB2 |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ACTN2;RYR2;CACNG4;ITGA10;LAMA2;DSC2;CACNB4;CACNG6;EMD |
| Dilated cardiomyopathy | IGF1;LAMA2;SLC8A1;MYBPC3;SGCA;ADRB1;Adcy4;CACNB1;SGCG |
CACNG8 has several biochemical functions, for example, channel regulator activity, voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CACNG8 itself. We selected most functions CACNG8 had, and list some proteins which have the same functions with CACNG8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| channel regulator activity | CACNG7A;SLC9A3R2;CACNG7;CACNG8;CNIH3;CACNG2B;CACNG2A;CACNG4;CACNG2 |
| voltage-gated calcium channel activity | GRM7;CACNB4B;CACNB3A;CACNA1D;PKD2;CATSPER3;TPC3;ATP6V0CB;CACNG1A |
CACNG8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CACNG8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CACNG8.
- Q&As
- Reviews
Q&As (7)
Ask a questionCACNG8 primarily interacts with the alpha-1 subunit of calcium channels and may have interactions with other proteins in the channel complex.
CACNG8 is mainly expressed in neural tissues, particularly in the brain.
By its interaction, CACNG8 can influence the channel's gating dynamics, its cellular localization, and calcium ion permeation characteristics.
Genetic alterations in the CACNG8 gene can modify its regulatory function, potentially influencing the dynamics and behavior of associated calcium channels.
Variations or anomalies in CACNG8 have been linked to certain neurological disorders, but detailed research is necessary for specific correlations.
CACNG8 acts as an auxiliary subunit, influencing the modulation of activity, trafficking, and surface expression of voltage-gated calcium channels.
Methods like mass spectrometry can be utilized to uncover potential post-translational modifications on CACNG8.
Customer Reviews (3)
Write a reviewConsistent and reproducible protein characterization.
Outstanding technical support for our protein experiments.
Affordable pricing for high-quality protein analysis.
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