cant1
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  • Official Full Name
  • calcium activated nucleotidase 1
  • Background
  • This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.
  • Synonyms
  • CANT1; calcium activated nucleotidase 1; soluble calcium-activated nucleotidase 1; SCAN 1; SHAPY; Soluble Ca Activated Nucleotidase; isozyme 1; Apyrase; Apyrase homolog; Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase; CANT 1; CANT1_HUMAN; Putative MAPK activating protein PM09; Putative MAPK-activating protein PM09; Putative NF kappa B activating protein 107; Putative NF-kappa-B-activating protein 107; SCAN-1; Soluble Ca activated nucleotidase isozyme 1; Soluble calcium activated nucleotidase 1; Soluble calcium activated nucleotidase SCAN 1; soluble Ca-activated nucleotidase, isozyme 1; soluble calcium-activated nucleotidase SCAN-1; Ca2+-dependent endoplasmic; DBQD; SCAN1
Cat.#:CANT1-0348HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CANT1 Protein, GST-Tagged
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Cat.#:CANT1-585HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CANT1 Protein, His-tagged
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Cat.#:Cant1-586MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cant1 Protein, His-tagged
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Cat.#:CANT1-1338HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Calcium Activated Nucleotidase 1, His-tagged
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Cat.#:CANT1-489HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CANT1 Protein, His-tagged
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Cat.#:CANT1-7348HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CANT1, Fc tagged
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Cat.#:CANT1-2685MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CANT1 Protein
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Cat.#:CANT1-1113RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CANT1 Protein
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Cat.#:CANT1-3222CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CANT1
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Cat.#:CANT1-1455HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CANT1 cell lysate
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Cat.#:CANT1-1597HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CANT1 cell lysate
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Involved Pathway

CANT1 involved in several pathways and played different roles in them. We selected most pathways CANT1 participated on our site, such as Purine metabolism, Pyrimidine metabolism, UTP and CTP dephosphorylation II, which may be useful for your reference. Also, other proteins which involved in the same pathway with CANT1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Purine metabolism
POLR2E; NT5C2; NUDT9; PDE4D; PAPSS2A; ADCY2B; CECR1A; NME2; POLR2K; NUDT2
Pyrimidine metabolism
POLR1C; POLE2; TK1; NME3; TRR1; PRIM2; NT5E; NT5C3B; CMPK1; POLR2J3
UTP and CTP dephosphorylation II
CANT1

Protein Function

CANT1 has several biochemical functions, for example, calcium ion binding, guanosine-diphosphatase activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CANT1 itself. We selected most functions CANT1 had, and list some proteins which have the same functions with CANT1. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PCDH19; FKBP14; PCDH2G12; SULF1; GAS6; MMP14B; PITPNM3; HPCAL1; SLC24A5; CD69
Function guanosine-diphosphatase activity
Related Protein CANT1A; ENTPD5; CANT1B; CANT1
Function signal transducer activity
Related Protein EDNRAB; PPP5C; GNB5; GNB2; FPR-RS3; GPR152; VMN1R41; TAS2R201.1; OLFR486; GNA14
Function uridine-diphosphatase activity
Related Protein ENTPD5; ENTPD4; CANT1; ENTPD6; CANT1A; CANT1B

CANT1 Related Articles

Manque, PA; Woehlbier, U; et al. Identification and Characterization of a Novel Calcium-Activated Apyrase from Cryptosporidium Parasites and Its Potential Role in Pathogenesis. PLOS ONE 7:-(2012).
Zarlenga, DS; Nisbet, AJ; et al. A calcium-activated nucleotidase secreted from Ostertagia ostertagi 4th-stage larvae is a member of the novel salivary apyrases present in blood-feeding arthropods. PARASITOLOGY 138:333-343(2011).