CAPN12 Protein, calpain 12

CAPN12

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CAPN12

Official Full Name calpain 12
Background The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012]
Synonyms CAPN12; calpain 12; calpain-12; CANP 12; calcium-activated neutral proteinase 12;
    • Species :
    • Human
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CAPN12-0359H Recombinant Human CAPN12 Protein, GST-Tagged Wheat Germ GST
    Human CAPN12-390H Recombinant Human CAPN12 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Zebrafish CAPN12-5372Z Recombinant Zebrafish CAPN12 Mammalian Cell His

    CAPN12 involved in several pathways and played different roles in them. We selected most pathways CAPN12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPN12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    CAPN12 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPN12 itself. We selected most functions CAPN12 had, and list some proteins which have the same functions with CAPN12. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PADI6; EML1; PCDHB16; CDH1; MFGE8A; EFCAB4A; PKD1L2; MYL12B; MMP15; GALNT3
    calcium-dependent cysteine-type endopeptidase activity CAPN2; PEF1; CAPN13; CAPNS1B; PDCD6; CAPN12; CAPN5A; CAPN3A; CAPN1A; CAPN3
    cysteine-type peptidase activity USP27X; FAM105B; CAPN3A; CAPN2L; CASP5; CAPN1A; CTSL1; CASP6L1; OTUD7A; CASP6
    hydrolase activity METAP2B; OVCH2; HTRA1A; GBP3; AGBL1; FIGNL1; ATP13A; PRSS59.2; ASPG; USP43A
    peptidase activity SPCS3; REN2; CAPN3A; GZMF; TMPRSS5; CTSH; IHHA; LTA4H; ELANE; ADAM25

    CAPN12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAPN12 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAPN12.

    Comitato, A; Sanges, D; et al. Activation of Bax in Three Models of Retinitis Pigmentosa. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:3555-3561(2014).
    Samanta, S; Ghoshal, A; et al. Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis. PLOS ONE 7:-(2012).

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