capn12
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  • Official Full Name
  • calpain 12
  • Background
  • The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012]
  • Synonyms
  • CAPN12; calpain 12; calpain-12; CANP 12; calcium-activated neutral proteinase 12;
Cat.#:CAPN12-0359HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CAPN12 Protein, GST-Tagged
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Cat.#:CAPN12-390HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CAPN12 Protein, MYC/DDK-tagged
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Cat.#:CAPN12-5372ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CAPN12
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Protein Function

CAPN12 has several biochemical functions, for example, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CAPN12 itself. We selected most functions CAPN12 had, and list some proteins which have the same functions with CAPN12. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein FBLN1; DSC2; VCANB; CBL; PCDH15A; PCDH2AB9; PCDH1A3; TNNC1A; PLCH2; SYT11A
Function calcium-dependent cysteine-type endopeptidase activity
Related Protein CAPN2; CAPN13; CAPN5; PDCD6; CAPN3A; SOLH; CAPNS1A; CAPN10; CAPN11; CAPN1B
Function cysteine-type peptidase activity
Related Protein SENP3A; OTUD5A; CASP7; OTUD6B; USP12A; CTLA2B; PSD; DUB1; SENP7B; USP9X
Function hydrolase activity
Related Protein PROCA; PEO1; C6AST3; HE2; Chil3; TIGARA; HAGHL; THTPA; PXYLP1; ABCB1A
Function peptidase activity
Related Protein PROCA; AGA; UCHL3; PAPPAB; ADAMTS4; BAP1; IHHA; Reln; USP27X; NAPSA

CAPN12 Related Articles

Comitato, A; Sanges, D; et al. Activation of Bax in Three Models of Retinitis Pigmentosa. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:3555-3561(2014).
Samanta, S; Ghoshal, A; et al. Sialoglycosylation of RBC in Visceral Leishmaniasis Leads to Enhanced Oxidative Stress, Calpain-Induced Fragmentation of Spectrin and Hemolysis. PLOS ONE 7:-(2012).