Recombinant Human CAPN12 Protein, GST-Tagged

• Cat.No.: CAPN12-0359H
• Product Overview: Human CAPN12 full-length ORF (AAI53094.1, 1 a.a. - 719 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 105.49 kDa
• AA Sequence: MASSSGRVTIQLVDEEAGVGAGRLQ LFRGQSYEAIRAACLDSGILFRDPY FPAGPDALGYDQLGPDSEKAKGVKW MRPHEFCAEPKFICEDMSRTDVCQG SLGNCWFLAAAASLTLYPRLLRRVV PPGQDFQHGYAGVFHFQLWQFGRWM DVVVDDRLPVREGKLMFVRSEQRNE FWAPLLEKAYAKLHGSYEVMRGGHM NEAFVDFTGGVGEVLYLRQNSMGLF SALRHALAKESLVGATALSDRGEYR TEEGLVKGHAYSITGTHKVFLGFTK VRLLRLRNPWGCVEWTGAWSDSCPR WDTLPTECRDALLVKKEDGEFWMEL RDFLLHFDTVQICSLSPEVLGPSPE GGGWHVHTFQGRWVRGFNSGGSQPN AETFWTNPQFRLTLLEPDEEDDEDE EGPWGGWGAAGARGPARGGRTPKCT VLLSLIQRNRRRLRAKGLTYLTVGF HVFQIPEELLGLWDSPRSHALLPRL LRADRSPLSARRDVTRRCCLRPGHY LVVPSTAHAGDEADFTLRVFSERRH TAVEIDDVISADLQSLQGPYLPLEL GLEQLFQELAGEEEELNASQLQALL SIALEPARAHTSTPREIGLRTCEQL LQCFGHGQSLALHHFQQLWGYLLEW QAIFNKFDEDTSGTMNSYELRLALN AAGFHLNNQLTQTLTSRYRDSRLRV DFERFVSCVAHLTCIFCHCSQHLDG GEGVICLTHRQWMEVATFS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CAPN12 calpain 12 [ Homo sapiens ]
• Official Symbol: CAPN12
• Synonyms: CAPN12; calpain 12
• Gene ID: 147968
• mRNA Refseq: NM_144691
• Protein Refseq: NP_653292
• MIM: 608839
• UniProt ID: Q6ZSI9