|Official Full Name||caspase 8 associated protein 2|
|Background||This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]|
|Synonyms||CASP8AP2; caspase 8 associated protein 2; CED-4; FLASH; RIP25; CASP8-associated protein 2; human FLASH; FLASH homolog RIP25; FLICE associated huge; CASP8 associated protein 2; FLICE-associated huge protein;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CASP8AP2 involved in several pathways and played different roles in them. We selected most pathways CASP8AP2 participated on our site, such as TNF-alpha NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CASP8AP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|TNF-alpha NF-kB Signaling Pathway||ZFAND5A; CAPN3A; SMARCA4A; NLRP4E; TRAF4A; SMARCC1; SMARCB1A; CASP8AP2; MTIF2; IKBKAP|
CASP8AP2 has several biochemical functions, for example, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CASP8AP2 itself. We selected most functions CASP8AP2 had, and list some proteins which have the same functions with CASP8AP2. You can find most of the proteins on our site.
|DNA binding||THRAA; LEF1; RIMKLB; HNRPK; KCNA3; ZNF266; TBX16; CDX1B; MLXIPL; ARHGAP35|
CASP8AP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CASP8AP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CASP8AP2.