cbfa2t2
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  • Official Full Name
  • core-binding factor, runt domain, alpha subunit 2; translocated to, 2
  • Background
  • In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5-region of the RUNX1 (AML1) gene fused to the 3
  • Synonyms
  • CBFA2T2; core-binding factor, runt domain, alpha subunit 2; translocated to, 2; protein CBFA2T2; MTGR1; ZMYND3; MTG8-like protein; MTG8-related protein 1; ETO homolog on chromosome 20; ETO homologous on chromosome 20; myeloid translocation-related protein
Cat.#:CBFA2T2-0451HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CBFA2T2 Protein, GST-Tagged
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Cat.#:CBFA2T2-2776MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CBFA2T2 Protein
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Cat.#:CBFA2T2-1881CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CBFA2T2
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Cat.#:CBFA2T2-7817HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CBFA2T2 293 Cell Lysate
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Protein Function

CBFA2T2 has several biochemical functions, for example, metal ion binding, protein binding, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CBFA2T2 itself. We selected most functions CBFA2T2 had, and list some proteins which have the same functions with CBFA2T2. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein ZNF789; CYBASC3; RSAD2; PVALB8; ZDHHC3A; ZC3H13; CAT; ZNF580; IRF2BP2A; ATP2C1
Function protein binding
Related Protein OSBPL3; C15orf57; LDB3; NPBWR2; ZNF205; TMEM30A; STX3; NUAK1; FRS3; EXOSC2
Function transcription corepressor activity
Related Protein KLF12; ZNF136; CCAR1; RBFOX2; ZFPM2; AEBP2; HDAC9; BASP1; TDP2; NPAT
Function transcription factor activity, sequence-specific DNA binding
Related Protein STAT1A; ZFP639; IRF2; GRHL2A; BATF3; FOXP1B; FOXN4; GAS7; MNX2B; CBFB

Interacting Protein

CBFA2T2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBFA2T2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBFA2T2.
MDFI; PRDM14; TCP1; PDP1; ZNF652; LBP; ATN1