• Official Full Name
  • CD248 molecule, endosialin
  • Background
  • Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
  • Synonyms
  • CD248; CD248 molecule, endosialin; TEM1; CD164L1; endosialin; 2610111G01Rik; CD164 sialomucin-like 1; CD248 antigen, endosialin; tumor endothelial marker 1;
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD248 Protein, GST-Tagged
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Cd248 Protein, His-tagged, Biotinylated
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD248, GST-tagged
Source (Host):NS0Species:Human
Product nameRecombinant Human CD248 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CD248 Protein
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey CD248 Protein
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey CD248 Protein, hIgG1-tagged
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey CD248 Protein, hIgG4-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD248 Protein, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human CD248 cell lysate

Protein Function

CD248 has several biochemical functions, for example, calcium ion binding, carbohydrate binding, extracellular matrix binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD248 itself. We selected most functions CD248 had, and list some proteins which have the same functions with CD248. You can find most of the proteins on our site.
Related Protein
Function calcium ion binding
Related Protein CA; S100A10; DSC2L; SYT5; CALB2; NOTCH3; PCDHGB3; PLS1; BMP1A; SLC25A12
Function carbohydrate binding
Related Protein CLEC4D; CLEC2D; C15orf24; GALNT10; CLEC1A; LGALS3; CD209B; LGALS4; CLEC18B; REG3G
Function extracellular matrix binding
Related Protein DMP1; SPP1; CYR61; SID4; VEGFA; ITGB3; ITGAV; GPR56; SPARC; FBLN2
Function molecular_function
Related Protein UBL7B; FBXO43; WDR65; SH3D21; AARSD1; CCDC85AL; RASSF10; SOSTDC1A; RTN2B; GM4307

Interacting Protein

CD248 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD248 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD248.

CD248 Related Articles

Li, CS; Wang, JY; et al. Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer. ONCOTARGET 5:6994-7012(2014).
Li, CS; Chacko, AM; et al. Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model. CANCER BIOLOGY & THERAPY 15:443-451(2014).