cd2bp2
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  • Official Full Name
  • CD2 (cytoplasmic tail) binding protein 2
  • Background
  • This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.
  • Synonyms
  • CD2BP2; CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; LIN1; PPP1R59; protein phosphatase 1; regulatory subunit 59; Snu40; FWP010; U5 snRNP 52K protein; CD2 cytoplasmic domain-binding protein 2; protein phosphatase 1, regulatory subunit 59; U5-52K
Cat.#:CD2BP2-0775HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CD2BP2 Protein, GST-Tagged
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Cat.#:CD2BP2-3070MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CD2BP2 Protein
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Cat.#:CD2BP2-735RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CD2BP2 Protein, His-tagged
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Cat.#:CD2BP2-11196ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CD2BP2
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Cat.#:CD2BP2-175HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human CD2BP2 lysate
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Involved Pathway

CD2BP2 involved in several pathways and played different roles in them. We selected most pathways CD2BP2 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD2BP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
SNAPC1B; RARGA; ZKSCAN1; ZNF334; NFIA; MED13B; TRMT11; ZNF202; ZNF254; ZFP1
Processing of Capped Intron-Containing Pre-mRNA
SF3B4; HNRNPR; NUDT21; RNPS1; HNRNPA0A; HNRNPA0; ZCRB1; DNAJC8; CSTF2; HNRNPH2
mRNA Splicing
YBX1; HNRNPR; HNRNPA0A; TTC6; DNAJC8; HNRPL; HNRNPH1L; HNRNPH2; PDCD7; HNRNPA2B1
mRNA Splicing - Major Pathway
SFRS3A; SUGP1; YBX1; HNRNPA0L; SF3B4; HNRNPA0A; PTBP1; RBM5; PCBP2; SF3B2
mRNA processing
SFPQ; CELF4; CD2BP2; VPRBP; TXNL4A; SUGP2; ZFP622; SF3B4; WBP4; FAM120B

Protein Function

CD2BP2 has several biochemical functions, for example, protein binding, ribonucleoprotein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD2BP2 itself. We selected most functions CD2BP2 had, and list some proteins which have the same functions with CD2BP2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein KRTAP10-4; SOX7; TUFM; FANCI; TOPORS; IMP4; RBMX2; WDR74; GSTM4; RXFP1
Function ribonucleoprotein complex binding
Related Protein SECISBP2; WDR12; ITCH; CKAP5; PRPF31; BOP1; RNASEL; CD2BP2; PIGC; PRMT5

Interacting Protein

CD2BP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD2BP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD2BP2.
CD2; PRPF6