Recombinant Human CD2BP2 Protein, GST-Tagged

• Cat.No.: CD2BP2-0775H
• Product Overview: Human CD2BP2 full-length ORF (AAH00495, 1 a.a. - 341 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 63.25 kDa
• AA Sequence: MPKRKVTFQGVGDEEDEDEIIVPKK KLVDPVAGSGGPGSRFKGKHSLDSD EEEDDDDGGSSKYDILASEDVEGQE AATLPSEGGVRITPFNLQEEMEEGH FDADGNYFLNRDAQIRDSWLDNIDW VKIRERPPGQRQASDSEEEDSLGQT SMSAQALLEGLLELLLPRETVAGAL RRLGARGGGKGRKGPGQPSSPQRLD RLSGLADQMVARGNLGVYQETRERL AMRLKGLGCQTLGPHNPTPPPSLDM FAEELAEEELETPTPTQRGEAESRG DGLVDVMWEYKWENTGDAELYGPFT SAQMQTWVSEGYFPDGVYCRKLDPP GGQFYNSKRIDFDLYT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CD2BP2 CD2 (cytoplasmic tail) binding protein 2 [ Homo sapiens ]
• Official Symbol: CD2BP2
• Synonyms: CD2BP2; CD2 (cytoplasmic tail) binding protein 2; CD2 antigen (cytoplasmic tail) binding protein 2; CD2 antigen cytoplasmic tail-binding protein 2; LIN1; PPP1R59; protein phosphatase 1; regulatory subunit 59; Snu40; U5 snRNP 52K protein; CD2 cytoplasmic domain-binding protein 2; protein phosphatase 1, regulatory subunit 59; FWP010; U5-52K
• Gene ID: 10421
• mRNA Refseq: NM_001243646
• Protein Refseq: NP_001230575
• MIM: 604470
• UniProt ID: O95400