cdca8
Share
  • Official Full Name
  • cell division cycle associated 8
  • Background
  • This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis;and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule;stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this;gene are found on chromosomes 7, 8 and 16.
  • Synonyms
  • CDCA8; cell division cycle associated 8; borealin; BOR; DasraB; FLJ12042; MESRGP; Dasra B; dasra-B; hDasra-B; cell division cycle-associated protein 8; pluripotent embryonic stem cell-related gene 3 protein; FLJ10468
Cat.#:CDCA8-0965HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDCA8 Protein, GST-Tagged
+Inquiry
Cat.#:CDCA8-11027HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDCA8, His-tagged
+Inquiry
Cat.#:CDCA8-27492THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDCA8, His-tagged
+Inquiry
Cat.#:CDCA8-3526HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Cell Division Cycle Associated 8, His-tagged
+Inquiry
Cat.#:CDCA8-3159MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CDCA8 Protein
+Inquiry
Cat.#:CDCA8-1287RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CDCA8 Protein
+Inquiry
Cat.#:CDCA8-1832ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDCA8
+Inquiry
Cat.#:CDCA8-324HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CDCA8 cell lysate
+Inquiry

Involved Pathway

CDCA8 involved in several pathways and played different roles in them. We selected most pathways CDCA8 participated on our site, such as Aurora B signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDCA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Aurora B signaling
EVI5; KIF2C; RACGAP1; NDC80; CENPA; INCENP; SMC4; DES; AURKB; NCAPD2
Cell Cycle
MSH5; NEK9; SSNA1; PDS5B; KIF2B; BLZF1; YWHAH; GINS3; NDEL1; ORC1
Cell Cycle, Mitotic
CDK11B; GOLGA2; MASTL; H3F3B.1; CENPI; CEP70; CENPQ; CTDNEP1A; SKA2; TUBG2
M Phase
GORASP1; NIPBLB; CENPQ; KIF2A; GORASP2; NEK7; USO1; CENPN; TMPO; ARPP19B
Mitotic Anaphase
CENPN; RCC2; AHCTF1; NDEL1A; CDCA5; NUF2; CDCA8; NDEL1B; CENPC1; CENPK
Mitotic Metaphase and Anaphase
PDS5B; NDEL1; WAPAL; CENPC1; SPC25; ZWINT; LEMD3; NSL1; SPC24; ERCC6L
Mitotic Prometaphase
NDEL1B; PDS5A; SGOL1; NUF2; PANE1; PDS5B; SKA2; INCENP; AHCTF1; SPC25
RHO GTPase Effectors
CLIP1; DSN1; WIPF2; BAIAP2; ERCC6L; MKL1B; MIS12; NOXO1A; RCC2; RHPN2

Protein Function

CDCA8 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDCA8 itself. We selected most functions CDCA8 had, and list some proteins which have the same functions with CDCA8. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein GRHL3; RFPL3; NSMCE1; KDR; NME1; IRF3; SLC39A13; RNF183; PDS5B; TESC

Interacting Protein

CDCA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDCA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDCA8.
BIRC5; AURKB; BIRC5