• Official Full Name
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39)
  • Background
  • Cyclin-dependent kinases (CDKs) are serine/threonine kinases that are activated by cyclins and govern eukaryotic cell cycle progression. While CDK5 shares high sequence homology with its family members, it is thought mainly to function in postmitotic neur
  • Synonyms
  • CDK5R2; cyclin-dependent kinase 5, regulatory subunit 2 (p39); cyclin-dependent kinase 5 activator 2; NCK5AI; neuronal CDK5 activator isoform; P39; p39nck5ai; p39I; CDK5 activator 2; cyclin-dependent kinase 5 regulatory subunit 2; cyclin-dependent kinase
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDK5R2 Protein, GST-Tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CDK5R2 Protein
Source (Host):Species:Human
Product nameRecombinant Human CDK5R2 cell lysate

Involved Pathway

CDK5R2 involved in several pathways and played different roles in them. We selected most pathways CDK5R2 participated on our site, such as Fanconi anemia pathway, Homologous recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK5R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fanconi anemia pathway
Homologous recombination
RPA1; RAD51; RAD52; TOP3B; MUS81; RPA4; RPA3; POLD1; RAD51L1; RAD54B

Protein Function

CDK5R2 has several biochemical functions, for example, DNA binding, DNA topoisomerase activity, DNA topoisomerase type I activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK5R2 itself. We selected most functions CDK5R2 had, and list some proteins which have the same functions with CDK5R2. You can find most of the proteins on our site.
Related Protein
Function DNA binding
Related Protein ZNF444; SIM2; TRIM27; RAD51L3; POU3F3; NR1D4A; NFRKB; ZNF484; SP6; FOXQ1B
Function DNA topoisomerase activity
Related Protein CDK5R2; TOP3B
Function DNA topoisomerase type I activity
Related Protein TOP3A; TOP3B; CDK5R2; TOP1MT; TOP1; TOP1L
Function poly(A) RNA binding
Related Protein FDPS; NDUFV3; RPL11; RPL7L1; TUFM; DDX23; RRS1; RPUSD3; SNRPD1; AASS
Function protein binding
Related Protein FGF1; LGI4; DVL2; SLAMF1; MXD4; NACA; F2R; KRT1; SLC7A1; RMND1

Interacting Protein

CDK5R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK5R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK5R2.