• Official Full Name
  • chromatin assembly factor 1, subunit B (p60)
  • Background
  • Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
  • Synonyms
  • CHAF1B; chromatin assembly factor 1, subunit B (p60); chromatin assembly factor 1 subunit B; CAF 1; CAF1; CAF1A; CAF1P60; Chromatin assembly factor I; p60 subunit; human chromatin assembly factor I p60 subunit; M phase phosphoprotein 7; MPHOSPH7; MPP7; CA
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CHAF1B Protein, GST-Tagged
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Chaf1b protein, His & T7-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CHAF1B
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CHAF1B
Source (Host):Species:Human
Product nameRecombinant Human CHAF1B 293 Cell Lysate

Protein Function

CHAF1B has several biochemical functions, for example, chromatin binding, histone binding, unfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHAF1B itself. We selected most functions CHAF1B had, and list some proteins which have the same functions with CHAF1B. You can find most of the proteins on our site.
Related Protein
Function chromatin binding
Related Protein ATF5; PATZ1; WDHD1; TOP2A; JDP2; HDAC4; PDX1; TSHZ3; POLD1; ZKSCAN3
Function histone binding
Related Protein IPO7; USP49; BRDT; HIST2H3C1; CHD2; NCL; SFMBT1; CTSL1; RNF168; L3MBTL1
Function unfolded protein binding
Related Protein DNAJA4; HSPA5; NAP1L4; TMEM67; GRXCR2; PFDN6; HSPA1A; CCT7; NDUFAF1; SSUH2.2

Interacting Protein

CHAF1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHAF1B here. Most of them are supplied by our site. Hope this information will be useful for your research of CHAF1B.
HIST1H3D; CHAF1A; CBX5; env; CNOT6L; ASF1B; Aff1; h3-catd; MYC; env