CHD6 Protein, chromodomain helicase DNA binding protein 6


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Official Full Name chromodomain helicase DNA binding protein 6
Background Chromosomal DNA of eukaryotic cells is compacted by nuclear proteins to form chromatin, an organized nucleoprotein structure that can inhibit gene expression. Several multisubunit protein complexes exist to remodel the chromatin to allow patterns of cell type-specific gene expression. The protein encoded by this gene is thought to be a core member of one or more of these complexes. The encoded protein, which is a member of the SNF2/RAD54 helicase family, contains two chromodomains, a helicase domain, and an ATPase domain.
Synonyms CHD6; chromodomain helicase DNA binding protein 6; chromodomain-helicase-DNA-binding protein 6; CHD5; dJ620E11.1; FLJ22369; KIAA1335; RIGB; ATP dependent helicase CHD6; ATP-dependent helicase CHD6; CHD-6; CHD6_HUMAN; Radiation induced gene B protein; Radiation-induced gene B protein; RP4-620E11.2; OTTHUMP00000031013; helicase C-terminal domain- and SNF2 N-terminal domain-containing protein
    • Species :
    • Mouse
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse CHD6-3381M Recombinant Mouse CHD6 Protein Mammalian Cell His

    CHD6 involved in several pathways and played different roles in them. We selected most pathways CHD6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CHD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    CHD6 has several biochemical functions, for example, ATP binding, ATP-dependent helicase activity, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHD6 itself. We selected most functions CHD6 had, and list some proteins which have the same functions with CHD6. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PMELA; MST1R; PSMC3; CDK15; AKT2L; TSSK4; WEE2; DDX19B; PLK1; NMRK1
    ATP-dependent helicase activity TTF2; RECQL5; CHD6; BLM; DHX36; DHX37; RTEL1; SNRNP200; CHD4A; ERCC6L2
    DNA binding TIGD5; PAX2; FOXJ1; ZNF333; SUB1A; ZNF496; RUNX1T1; TFDP1A; PURBB; ZBED3
    DNA-dependent ATPase activity RAD51B; SMARCA2; TOP2A; TTF2; CHD8; CHD6; SMARCA4; RAD51C; ERCC2; DDX11
    helicase activity DHX34; BLM; DDX58; CHD8; PL10; CHD7; SETX; CHD9; MOV10B.2; ACTG2
    hydrolase activity Aadacl3; DDX3; CMBL; MMP14B; FIGNL1; GDPGP1; CDC14AB; TDRD12; PRSS41; PLCD3A
    nucleic acid binding GFI1AB; BLM; PABPC1B; ZFP458; SREK1IP1; MTERF2; MSI2A; EIF2C3; ZFP239; ZCCHC12
    nucleotide binding NUBP1; MSI2A; MKI67IP; DNM1B; RAP1AA; OXSR1B; ERBB3A; DHX36; MYO15; LOC81691
    transcription cofactor binding FOXO3; CHD6; KLF4; TRP53

    CHD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHD6.


    Thomas, RH; Zhang, LM; et al. CHD2 myoclonic encephalopathy is frequently associated with self-induced seizures. NEUROLOGY 84:951-958(2015).
    Yamada, M; Sato, N; et al. Association of the Chromodomain Helicase DNA-Binding Protein 4 (CHD4) Missense Variation p.D140E with Cancer: Potential Interaction with Smoking. GENES CHROMOSOMES & CANCER 54:122-128(2015).

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