CHMP4C Protein, CHMP4C charged multivesicular body protein 4C [ Homo sapiens ]


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Official Full Name CHMP4C charged multivesicular body protein 4C [ Homo sapiens ]
Background CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Synonyms Charged multivesicular body protein 4c; CHM4C_HUMAN; CHMP4c; Chromatin-modifying protein 4c; hSnf7-3; hVps32-3; SNF7 homolog associated with Alix 3; SNF7-3; Vacuolar protein sorting-associated protein 32-3; Vps32-3
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHMP4C-11188H Recombinant Human CHMP4C, His-tagged E.coli His
    Human CHMP4C-7531HCL Recombinant Human CHMP4C 293 Cell Lysate HEK293 N/A
    Mouse CHMP4C-3409M Recombinant Mouse CHMP4C Protein Mammalian Cell His
    Rhesus Macaque CHMP4C-851R Recombinant Rhesus monkey CHMP4C Protein, His-tagged Mammalian Cell His
    Chicken CHMP4C-4331C Recombinant Chicken CHMP4C Mammalian Cell His
    Zebrafish CHMP4C-2568Z Recombinant Zebrafish CHMP4C Mammalian Cell His

    CHMP4C involved in several pathways and played different roles in them. We selected most pathways CHMP4C participated on our site, such as Budding and maturation of HIV virion, Cellular responses to stress, Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHMP4C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Budding and maturation of HIV virion PDCD6IP; gag; CHMP4C; VPS37A; PPIA; CHMP4B
    Cellular responses to stress HIST1H1D; UBN1; ATG7; HSPH1; CHMP4B; HIST1H1C; CHMP4C; EED; RBBP7; AGO3
    Disease DPF1; AMN; KREMEN1; TICAM1; CCR5; KPNA4; TRAT1; TLR10; KPNA3; HEY1
    Endocytosis EPS15; CHMP7; VPS26B; CDC42L; PIP5K1BB; GIT1; EHD1A; TGFBR1; BC2; HSP70L
    Endosomal Sorting Complex Required For Transport (ESCRT) VPS37A; SNF8; STAM2; CHMP4C; CHMP4B
    HIV Infection RCC1; CDK9; AP1M2; PACS1; TAF1L; NMT2; PSTPIP2; AP1S1; AP1G1; PSIP1
    Infectious disease CHMP4B; TAF1L; LTF; CCDC167; AP1G1; CPSF4; NMT2; KPNA3; ANTXR1; IPO5

    CHMP4C has several biochemical functions, for example, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHMP4C itself. We selected most functions CHMP4C had, and list some proteins which have the same functions with CHMP4C. You can find most of the proteins on our site.

    Function Related Protein
    protein binding LUC7L; GPRIN2; SUCLA2; FARSA; CUTA; DCD; FLI1; DOCK10; CTSK; SLC4A1
    protein homodimerization activity MCL1; HELT; STK10; VEGFB; PPP2R4; ZNF174; YARS2; SLC24A6; SLC14A2; ABP1

    CHMP4C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHMP4C here. Most of them are supplied by our site. Hope this information will be useful for your research of CHMP4C.

    USP8; 128872; USP54; STAMBP; PDCD6IP; IGHA1

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