chp
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  • Official Full Name
  • chemotaxis-inhibiting protein CHIPS
  • Background
  • This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein
  • Synonyms
  • chp; chemotaxis-inhibiting protein CHIPS; Chemotaxis inhibiting protein; secreted protein that specifically inhibits the activation of neutrophils and monocytes by binding to the formylated peptide receptor and the C5a receptor; blocks neutrophil migration towards the infection site and hinders the establishment of the initial
Cat.#:CHP-1261HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CHP Protein, GST-Tagged
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Cat.#:CHP-11197HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHP, GST-tagged
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Cat.#:CHP-2583HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Lcium Binding Protein P22, His-tagged
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Cat.#:CHP-1381RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CHP Protein
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Cat.#:CHP-7527HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CHP 293 Cell Lysate
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Involved Pathway

CHP involved in several pathways and played different roles in them. We selected most pathways CHP participated on our site, such as Alzheimers Disease, Calcium signaling in the CD4+ TCR pathway, Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHP were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alzheimers Disease
NDUFV1; GRIN2B; NDUFC1; CAPN2; FAS; MME; BAD; UQCRH; COX7C; PPP3R2
Calcium signaling in the CD4+ TCR pathway
RCAN1; POU2F1; CSF2; RCAN2; JUNB; AKAP5; BATF3; CHP; FKBP1A
Glycosaminoglycan metabolism
PRELP; B3GNT2; HAS3; FMODA; GPC1B; HAS1; CHP; CHST14; VCANB; GPC5A
Hyaluronan metabolism
CHP; HAS3; KIAA1199; HAS1; LYVE1; STAB2
Hyaluronan uptake and degradation
CHP; LYVE1; STAB2
Metabolism
PMVK; MED19; COX5B; NDUFAF5; SULT1C4; LYRM4; PTGDSA; MED25; ACOT11; ALOX5B.3
Metabolism of carbohydrates
SLC5A9; FMODA; SLC35B3; KHK; HS3ST6; UST; STAB2; PFKLB; GCKR; CHST14
Role of Calcineurin-dependent NFAT signaling in lymphocytes
FKBP8; RCAN1; RCAN2; CHP

Protein Function

CHP has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHP itself. We selected most functions CHP had, and list some proteins which have the same functions with CHP. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein MYL9; CELSR1; RAB11FIP4A; S100A12; CABP4; PCDH19; CAPSLA; TLL1; CAPRIN1A; PLA2G2D
Function calcium-dependent protein binding
Related Protein CALM1; S100A11; CASQ2; ANXA2; A2M; C9orf9; S100A6; MYO1D; PDCD6; SYT1
Function kinase binding
Related Protein TAX1BP1; TRIP6; JAKMIP2; LDHA; CDC6; TRADD; PFKM; CDC37; PER1; TOLLIP
Function microtubule binding
Related Protein EML1; CAMSAP1A; MAP1S; S100A8; EML2; PAFAH1B1B; NDEL1B; MID1; BCL2L11; MAP1B
Function potassium channel regulator activity
Related Protein KCNMB1; ARPP19; KCNE1; DPP10; KCNV1; ARPP19A; KCNIP2; KCNS3; SGK1; KCNE3
Function protein binding
Related Protein PBRM1; RPLP0; TXNL4A; RILP; PSEN2; AGPAT1; PNMA5; RARG; POLR3GL; GSS
Function protein kinase inhibitor activity
Related Protein SOCS9; WNK1; SH3BP5L; SH3BP5; NPM1; MBIP; CHP1; SOCS1A; CAMK2N1A; GMFG
Function transporter activity
Related Protein SLC15A3; SLCO1A6; NUTF2; Abcb1b; RBP4L; SLC13A5; SLC5A6A; APODA.1; RBP5; DYF-1

CHP Related Articles

Paniagua-Contreras, GL; Monroy-Perez, E; et al. Expression of enterotoxin-coding genes in methicillin-resistant Staphylococcus aureus strains isolated from Mexican haemodialysis patients. ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS 13:-(2014).
Saito, T; Wada, H; et al. High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine. VACCINE 32:5901-5907(2014).