chp
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  • Official Full Name
  • chemotaxis-inhibiting protein CHIPS
  • Background
  • This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein
  • Synonyms
  • chp; chemotaxis-inhibiting protein CHIPS; Chemotaxis inhibiting protein; secreted protein that specifically inhibits the activation of neutrophils and monocytes by binding to the formylated peptide receptor and the C5a receptor; blocks neutrophil migration towards the infection site and hinders the establishment of the initial
Cat.#:CHP-1261HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CHP Protein, GST-Tagged
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Cat.#:CHP-11197HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CHP, GST-tagged
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Cat.#:CHP-2583HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Lcium Binding Protein P22, His-tagged
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Cat.#:CHP-1381RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CHP Protein
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Cat.#:CHP-7527HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CHP 293 Cell Lysate
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Involved Pathway

CHP involved in several pathways and played different roles in them. We selected most pathways CHP participated on our site, such as Alzheimers Disease, Calcium signaling in the CD4+ TCR pathway, Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alzheimers Disease
ATP5D; NDUFA4L2; NDUFB9; RYR3; UQCRFS1; MME; CDK5; Atp5g2; APH1B; CALM4
Calcium signaling in the CD4+ TCR pathway
FKBP1A; POU2F1; BATF3; AKAP5; RCAN1; JUNB; CHP; RCAN2; CSF2
Glycosaminoglycan metabolism
SLC35D2; FMODA; KERA; B3GNT2; B3GNT2A; VCANB; CHST14; UST; GPC5A; OGN
Hyaluronan metabolism
KIAA1199; HAS3; STAB2; HAS1; LYVE1; CHP
Hyaluronan uptake and degradation
STAB2; LYVE1; CHP
Metabolism
ADHFE1; CYP2U1; CYP2AD2; Sult2a2; NAMPT; INSIG2; MED29; FAAH2; AZIN1; MED20
Metabolism of carbohydrates
SLC25A11; KIAA1199; TREH; B3GNT3; HS3ST6; LYVE1; SLC5A9; Gpc2; OXSR1; B3GAT2
Role of Calcineurin-dependent NFAT signaling in lymphocytes
RCAN1; RCAN2; CHP; FKBP8

Protein Function

CHP has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHP itself. We selected most functions CHP had, and list some proteins which have the same functions with CHP. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein ITSN2A; DSG4; LRP1; CRTAC1; PCDH1G2; PCDH7; ICN2; SPARC; SLIT3; LDLRB
Function calcium-dependent protein binding
Related Protein SYT1; MASP1; SELP; MBL2; RAC3; S100PBP; C9orf9; SEC31A; DMBT1; CHP1
Function kinase binding
Related Protein CDC6; PARK2; ABI2; C2orf44; WWC1; RPS3; WWC3; PRKAA1; PPP2R5A; DLG1
Function microtubule binding
Related Protein DYNC1I1; CCDC88A; JAKMIP2; KIF1C; KIF5A; GCAP14; PPP5C; JAKMIP1; MTUS2; CASC1
Function potassium channel regulator activity
Related Protein AMIGO1; ANK2; KCNMB2; KCNMB1; KCNIP2; CHP; SGK2A; ADRB2; DRD2; KCNE1
Function protein binding
Related Protein C16orf72; SSNA1; PHF17; ZFPM2; ANGPT2; SH2D1B; FAM113B; FRG1; PSPC1; INIP
Function protein kinase inhibitor activity
Related Protein SOCS3B; CAMK2N1A; TRIB1; GMFB; DUSP19; MBIP; SH3BP5B; SH3BP5LA; TAOK3; SOCS3A
Function transporter activity
Related Protein ATP5J; APODA.2; AP1S2; RBP2B; GOSR2; MUP17; TCIRG1; OSTB; SLC4A2B; TIMM10

CHP Related Articles

Paniagua-Contreras, GL; Monroy-Perez, E; et al. Expression of enterotoxin-coding genes in methicillin-resistant Staphylococcus aureus strains isolated from Mexican haemodialysis patients. ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS 13:-(2014).
Saito, T; Wada, H; et al. High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine. VACCINE 32:5901-5907(2014).