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Clvs2

Official Full Name

clavesin 2
Overview

This gene encodes a protein that belongs to the SEC14/CRAL-TRIO family of proteins. A similar protein in rat is thought to function in the endosomal pathway between early endosomes and mature lysosomes.
Synonyms

CLVS2; RLBP1L2; C6orf212; C6orf213; bA160A10.4; clavesin 2; clavesin-2; retinaldehyde binding protein 1-like 2;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

E. coli
E.coli
HEK293
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
His|SUMO
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CLVS2-7424HCL	Recombinant Human CLVS2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CLVS2-1030H	Recombinant Human CLVS2 Protein (1-327 aa), His-SUMO-tagged	E.coli	His/SUMO	1-327 aa	Inquiry
Human	CLVS2-100H	Recombinant Human CLVS2 protein, GST-tagged	E. coli	GST	265-327 aa	$319 / 25ug
Mouse	CLVS2-3616M	Recombinant Mouse CLVS2 Protein	Mammalian Cell	His		Inquiry
Mouse	CLVS2-1776M	Recombinant Mouse CLVS2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CLVS2-1776M-B	Recombinant Mouse CLVS2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CLVS2-923R	Recombinant Rhesus monkey CLVS2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	CLVS2-748R-B	Recombinant Rhesus Macaque CLVS2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CLVS2-748R	Recombinant Rhesus Macaque CLVS2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	CLVS2-3158Z	Recombinant Zebrafish CLVS2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Clvs2 involved in several pathways and played different roles in them. We selected most pathways Clvs2 participated on our site, such as Clathrin derived vesicle budding, Lysosome Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with Clvs2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Clathrin derived vesicle budding	SNX9A;NAPAB;CLINT1;YIPF6;TFR1B;HIP1RB;GAK;BLOC1S4;PPIAL4A
Lysosome Vesicle Biogenesis	CLVS2;CLVS1;AP4B1;BLOC1S1;DNASE2;AP1S3A;CTSZ
Membrane Trafficking	EXOC8;GJB5;SEC23IP;TRAPPC2L;BET1;CTAGE5;CNIH2;LMAN2;CNIH
Vesicle-mediated transport	PICALMB;SNF8;CLVS2;ARCN1B;TPD52L1;HIP1RB;TRAPPC6BL;COPZ1;SNX9B
trans-Golgi Network Vesicle Budding	TBC1D8B;BLOC1S4;FTH1B;FTH1A;TPD52L1;CLINT1;TCEAL4;DNASE2;SNX9A

Clvs2 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate binding, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Clvs2 itself. We selected most functions Clvs2 had, and list some proteins which have the same functions with Clvs2. You can find most of the proteins on our site.

Function	Related Protein
phosphatidylinositol-3,5-bisphosphate binding	CLVS1;WDR45L;WIPI1;COMMD1;SNX3;D6WSU116E;CLVS2;MAPKAP1;SH3PXD2B
transporter activity	NUP153;AP1B1;SLCO1D1;ATP5G1;SLC26A3;SLC15A4;LCN9;AP2S1;SLC2A15A

Clvs2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Clvs2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Clvs2.