CRB2 Protein, crumbs homolog 2 (Drosophila)

CRB2

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CRB2

Official Full Name crumbs homolog 2 (Drosophila)
Synonyms CRB2;crumbs homolog 2 (Drosophila);18688;ENSG00000148204;RP11-230L22.2;9q33.3;FLJ16786, FLJ38464;crumbs homolog 2;crumbs homolog 2;crumbs-like protein 2;
    • Species :
    • Mouse
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse CRB2-3881M Recombinant Mouse CRB2 Protein Mammalian Cell His

    CRB2 involved in several pathways and played different roles in them. We selected most pathways CRB2 participated on our site, such as Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hippo signaling pathway FZD5; CRB2; BMP4; AMH; INADL; NKD1; YWHAE; SMAD4; CRB1; BMP8B

    CRB2 has several biochemical functions, for example, contributes_to aspartic-type endopeptidase inhibitor activity, calcium ion binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CRB2 itself. We selected most functions CRB2 had, and list some proteins which have the same functions with CRB2. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to aspartic-type endopeptidase inhibitor activity CRB2
    calcium ion binding PPP3R1; PCDH1G22; SYTL1; CABP1B; PADI1; STIM2; PCDH1G30; CALML4A; S100A10A; EFCC1
    enzyme binding AKT1; PARP1; MAPT; PTPLA; HSPA2; TSPAN10; DIS3L; APBA3; LAMP1; PTEN

    CRB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CRB2.

    Ebarasi, L; Ashraf, S; et al. Defects of CRB2 Cause Steroid-Resistant Nephrotic Syndrome. AMERICAN JOURNAL OF HUMAN GENETICS 96:153-161(2015).
    Slavotinek, A; Kaylor, J; et al. CRB2 Mutations Produce a Phenotype Resembling Congenital Nephrosis, Finnish Type, with Cerebral Ventriculomegaly and Raised Alpha-Fetoprotein. AMERICAN JOURNAL OF HUMAN GENETICS 96:162-169(2015).

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