creg1
Share
  • Official Full Name
  • cellular repressor of E1A-stimulated genes 1
  • Background
  • The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
  • Synonyms
  • CREG1; cellular repressor of E1A-stimulated genes 1; cellular repressor of E1A stimulated genes , CREG; protein CREG1; CREG
Cat.#:CREG1-1104HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CREG1 Protein (Met1-Gln220), His-tagged
+Inquiry
Cat.#:CREG1-1857HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CREG1 Protein, GST-tagged
+Inquiry
Cat.#:CREG1-3329HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CREG1 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:CREG1-1043HTag:His
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human CREG1 Protein, His-tagged
+Inquiry
Cat.#:CREG1-227HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CREG1 Protein, His-tagged
+Inquiry
Cat.#:Creg1-1536MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Creg1 protein, His & T7-tagged
+Inquiry
Cat.#:Creg1-401MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Creg1, Fc tagged
+Inquiry
Cat.#:Creg1-531MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Creg1, His tagged
+Inquiry
Cat.#:Creg1-665MTag:His
Source (Host):NSO CellsSpecies:Mouse
Product nameRecombinant Mouse Creg1 Protein, His-tagged
+Inquiry
Cat.#:CREG1-5161ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CREG1
+Inquiry
Cat.#:CREG1-1069MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CREG1 cell lysate
+Inquiry
Cat.#:CREG1-1123MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse CREG1 cell lysate
+Inquiry

Involved Pathway

CREG1 involved in several pathways and played different roles in them. We selected most pathways CREG1 participated on our site, such as Senescence and Autophagy, which may be useful for your reference. Also, other proteins which involved in the same pathway with CREG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Senescence and Autophagy
IL24; RB1CC1; SLC39A1; ING2; SLC39A3; MAP1LC3B; RSL1D1; FKBP8; ING1; COL10A1

Protein Function

CREG1 has several biochemical functions, for example, FMN binding, oxidoreductase activity, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CREG1 itself. We selected most functions CREG1 had, and list some proteins which have the same functions with CREG1. You can find most of the proteins on our site.
Function
Related Protein
Function FMN binding
Related Protein CREG1; NOS1; POR; CREG2; TYW1B; HAO1; NOS3; MTRR; NOS2; PNPO
Function oxidoreductase activity
Related Protein HADHAB; HSD3B6; AOX3L1; SDR39U1; CYP2P10; FDFT1; DHRS13L1; CYP4A12A; SCD5; CYP2F2
Function transcription corepressor activity
Related Protein POU1F1; DRAP1; ZNF274; MYBBP1A; AEBP2; TRIM28; UBP1; NPAT; NR1H4; MXI1
Function transcription factor binding
Related Protein VDRA; PPP1R13BA; NKX3; KCTD1; GATA4; KEAP1; NFKBIA; RNF19A; PIM1; TRIB2

Interacting Protein

CREG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CREG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CREG1.
purT; glyA

CREG1 Related Articles

Yan, CH; Li, Y; et al. CREG1 ameliorates myocardial fibrosis associated with autophagy activation and Rab7 expression. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:353-364(2015).
Peng, CF; Han, YL; et al. OVEREXPRESSING CELLULAR REPRESSOR OF E1A-STIMULATED GENES PROMOTE HYPOXIA-INDUCED VEGF PARACRINE VIA HIF-1 IN MESENCHYMAL STEM CELLS. HEART 99:E24-E24(2013).