CRTAM
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Official Full Name
cytotoxic and regulatory T cell molecule
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Overview
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and;encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 (PubMed 18329370)). -
Synonyms
CRTAM; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule; CD355; class I MHC restricted T cell associated molecule; OTTHUMP00000231739; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus
- Cynomolgus monkey
- Homo sapiens (Human)
- Human
- Mouse
- Rhesus monkey
- E.coli
- E.coli expression system
- HEK293
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Fc
- GST
- hIgG1
- hIgG4
- His (Fc)
- Avi
- human|IgG1|Fc
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- CRTAM Related Articles
- CRTAM Related Research Area
CRTAM involved in several pathways and played different roles in them. We selected most pathways CRTAM participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with CRTAM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Adaptive Immune System | MOV10;NRG3;LCP2A;UBE2L6;RNF182;FAM49BA;CTSO;OSBPL1A;KIF2C |
Immune System | GM11711;LY86;KIF26A;TNFSF13B;LRR1;CNPY3;CHST13;TRIM69;KIF11 |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | CD300LB;CLEC2B;Siglece;NCR3LG1;SIGLEC8;TREM1;CD300LH;KIR2DS2;MICA |
CRTAM has several biochemical functions, for example, cell adhesion molecule binding, protein homodimerization activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CRTAM itself. We selected most functions CRTAM had, and list some proteins which have the same functions with CRTAM. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
cell adhesion molecule binding | NCR3;CADM3;NLGN1;NRXN1;DSP;CD1d1;SELL;CADM2A;NPTN |
protein homodimerization activity | ABCB10;STK25;INHBB;SYT16;FAM109B;CD226;BNIP3L;MAP3K10;IKZF4 |
receptor activity | GRIK3;CD33;CADM1A;ADIPOR1A;FPR3;TNFRSF11A;TREML2;CD200;NLGN3A |
receptor binding | ANKRD13C;APP;APOF;GLA;CNPY4;NRG2;NRG4;LRP6;POMC |
CRTAM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CRTAM here. Most of them are supplied by our site. Hope this information will be useful for your research of CRTAM.
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