Recombinant Human CRTAM Protein, His-tagged CRTAM-371H

Recombinant Human CRTAM Protein, His-tagged

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Recombinant Human CRTAM Protein, His-tagged

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Cat.No. : CRTAM-371H
Product Overview : Recombinant human CRTAM, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description : CRTAM, also known as cytotoxic and regulatory T-cell molecule, is a member of the immunoglobulin superfamily that complies with the structural characteristics of the JAM family of proteins and is phylogenetically more closely related to nectin-like proteins. It is a molecule involved in epithelial cell adhesion. This protein interacts with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
Source : Insect cell
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 31.0kDa (278aa)40-57KDa (SDS-PAGE under reducing conditions.)
AA Sequence : SLTNHTETIT VEEGQTLTLK CVTSLRKNSS LQWLTPSGFT IFLNEYPALK NSKYQLLHHS ANQLSITVPN VTLQDEGVYK CLHYSDSVSTKEVKVIVLAT PFKPILEASV IRKQNGEEHV VLMCSTMRSK PPPQITWLLG NSMEVSGGTL HEFETDGKKC NTTSTLIIHT YGKNSTVDCIIRHRGLQGRK LVAPFRFEDL VTDEETASDA LERNSLSSQD PQQPTSTVSV TEDSSTSEID KEEKEQTTQD PDLTTEANPQ YLGLARKKSGLEHHHHHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Absorbance at 280nm)
Gene Name : CRTAM cytotoxic and regulatory T cell molecule [ Homo sapiens ]
Official Symbol : CRTAM
Synonyms : CRTAM; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule; CD355; class I MHC restricted T cell associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule;
Gene ID : 56253
mRNA Refseq : NM_019604
Protein Refseq : NP_062550
MIM : 612597
UniProt ID : O95727
Chromosome Location : 11q24.1
Pathway : Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem;
Function : receptor binding;

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