Recombinant Human CRTAM Protein, His-tagged
Cat.No. : | CRTAM-371H |
Product Overview : | Recombinant human CRTAM, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | CRTAM, also known as cytotoxic and regulatory T-cell molecule, is a member of the immunoglobulin superfamily that complies with the structural characteristics of the JAM family of proteins and is phylogenetically more closely related to nectin-like proteins. It is a molecule involved in epithelial cell adhesion. This protein interacts with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 31.0kDa (278aa)40-57KDa (SDS-PAGE under reducing conditions.) |
AA Sequence : | SLTNHTETIT VEEGQTLTLK CVTSLRKNSS LQWLTPSGFT IFLNEYPALK NSKYQLLHHS ANQLSITVPN VTLQDEGVYK CLHYSDSVSTKEVKVIVLAT PFKPILEASV IRKQNGEEHV VLMCSTMRSK PPPQITWLLG NSMEVSGGTL HEFETDGKKC NTTSTLIIHT YGKNSTVDCIIRHRGLQGRK LVAPFRFEDL VTDEETASDA LERNSLSSQD PQQPTSTVSV TEDSSTSEID KEEKEQTTQD PDLTTEANPQ YLGLARKKSGLEHHHHHH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1mg/ml (determined by Absorbance at 280nm) |
Gene Name : | CRTAM cytotoxic and regulatory T cell molecule [ Homo sapiens ] |
Official Symbol : | CRTAM |
Synonyms : | CRTAM; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule; CD355; class I MHC restricted T cell associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; |
Gene ID : | 56253 |
mRNA Refseq : | NM_019604 |
Protein Refseq : | NP_062550 |
MIM : | 612597 |
UniProt ID : | O95727 |
Chromosome Location : | 11q24.1 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; |
Function : | receptor binding; |
Products Types
◆ Recombinant Protein | ||
CRTAM-1912H | Recombinant Human CRTAM Protein | +Inquiry |
CRTAM-1913H | Recombinant Human CRTAM Protein, GST-tagged | +Inquiry |
Crtam-23M | Recombinant Mouse Crtam Protein, His (Fc)-Avi-tagged | +Inquiry |
CRTAM-775C | Recombinant Cynomolgus monkey CRTAM Protein, Fc-tagged | +Inquiry |
CRTAM-119H | Recombinant Human CRTAM Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
CRTAM-2216HCL | Recombinant Human CRTAM cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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