cspg5
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  • Official Full Name
  • chondroitin sulfate proteoglycan 5 (neuroglycan C)
  • Background
  • The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • CSPG5; chondroitin sulfate proteoglycan 5 (neuroglycan C); chondroitin sulfate proteoglycan 5; NGC; Acidic leucine rich EGF like domain containing brain protein; Acidic leucine-rich EGF-like domain-containing brain protein; Caleb; CSPG5_HUMAN; MGC44034; Neuroglycan C; OTTHUMP00000164796; OTTHUMP00000164797; OTTHUMP00000210429
Cat.#:CSPG5-2015HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CSPG5 Protein, GST-tagged
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Cat.#:CSPG5-416HTag:His
Source (Host):CHO cellsSpecies:Human
Product nameRecombinant Human CSPG5, His-tagged
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Cat.#:Cspg5-340MTag:His
Source (Host):CHO cellsSpecies:Mouse
Product nameRecombinant Mouse Cspg5, His-tagged
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Cat.#:CSPG5-3984MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CSPG5 Protein
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Cat.#:Cspg5-1539RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Cspg5 protein, His-tagged
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Cat.#:CSPG5-1640RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CSPG5 Protein
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Cat.#:CSPG5-425CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CSPG5 Protein, His-tagged
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Cat.#:CSPG5-6284CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CSPG5
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Involved Pathway

CSPG5 involved in several pathways and played different roles in them. We selected most pathways CSPG5 participated on our site, such as A tetrasaccharide linker sequence is required for GAG synthesis, CS/DS degradation, Chondroitin sulfate biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSPG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
A tetrasaccharide linker sequence is required for GAG synthesis
Gpc2; B3GAT2; GPC5A; CSPG5B; VCAN; BGN; BGNB; GPC5; DCN; BCAN
CS/DS degradation
BGNA; VCANB; BGNB; VCAN; NCAN; DCN; BCAN; CSPG5; CSPG5B; CSPG4
Chondroitin sulfate biosynthesis
CSPG4; BGNB; BCAN; NCAN; CHST9; BGN; VCAN; CSPG5B; CSPG5; VCANB
Chondroitin sulfate/dermatan sulfate metabolism
UST; DSEL; CSPG5; BGNB; GPC1B; Gpc2; VCANB; BGNA; GPC5A; CSPG5B
Defective B3GALT6 causes EDSP2 and SEMDJL1
DCN; NCAN; GPC6; BGN; CSPG4; AGRN; VCAN; BCAN; GPC5; CSPG5
Defective B3GAT3 causes JDSSDHD
NCAN; BCAN; CSPG4; AGRN; CSPG5; GPC6; GPC5; BGN; VCAN; DCN
Defective B4GALT7 causes EDS, progeroid type
BGN; BCAN; NCAN; CSPG5; AGRN; DCN; GPC6; CSPG4; VCAN; GPC5
Defective CHST14 causes EDS, musculocontractural type
BCAN; BGN; CSPG4; DCN; CSPG5

Protein Function

CSPG5 has several biochemical functions, for example, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSPG5 itself. We selected most functions CSPG5 had, and list some proteins which have the same functions with CSPG5. You can find most of the proteins on our site.
Function
Related Protein
Function growth factor activity
Related Protein NTF3; GRN; BDNF; JAG1; BMP10; IL34; FGF18; COL20A1; PDGFC; FGF10B
Function protein binding
Related Protein COMMD5; G0S2; FAM195A; RAB4A; RFFL; TRIM25; PPP1CC; TGFBRAP1; AP3S1; VAT1L

Interacting Protein

CSPG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSPG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CSPG5.
Gopc

CSPG5 Related Articles

Ruiz, C; Li, JL; et al. Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients. PHYSICAL BIOLOGY 12:-(2015).
Ho, LTY; Harris, AM; et al. A comparison of glycosaminoglycan distributions, keratan sulphate sulphation patterns and collagen fibril architecture from central to peripheral regions of the bovine cornea. MATRIX BIOLOGY 38:59-68(2014).