CST2

  • Official Full Name

    cystatin SA

  • Overview

    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma.

  • Synonyms

    CST2;cystatin SA;cystatin-SA;cystatin 2;cystatin-2;cystatin S5;cystatin-S5;cysteine-proteinase inhibitor;salivary cysteine (thiol) protease inhibitor;MGC71924

Recombinant Proteins

  • Human
  • HEK293
  • Wheat Germ
  • Human Cells
  • E.coli
  • Mammalian Cells
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CST2-3214H Recombinant Human CST2 protein(Met1-Ala141), His-tagged HEK293 Human His 1-141 a.a.
CST2-195H Recombinant Human CST2 protein, His-tagged HEK293 Human His Trp21-Ala141
CST2-2024H Recombinant Human CST2 Protein, GST-tagged Wheat Germ Human GST
CST2-2240HCL Recombinant Human CST2 cell lysate Human Cells Human Non
CST2-1662H Recombinant Human CST2 protein, His-tagged E.coli Human His Trp21~Ala141
CST2-1843H Recombinant Human CST2 Protein (Trp21-Ala141), C-His tagged Mammalian Cells Human His Trp21-Ala141
CST2-190H Recombinant Human CST2 Protein, His-tagged HEK293 Human His 141
CST2-2234HF Recombinant Full Length Human CST2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 141 amino acids
CST2-3357H Recombinant Human CST2 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc

    Involved Pathway

    CST2 involved in several pathways and played different roles in them. We selected most pathways CST2 participated on our site, such as Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CST2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Salivary secretion ITPR1,Slc4a2,PRKG1,AMY1B,CST3,DMBT1,ATP1A3,ATP1A4,CST4,LYZ1

    Protein Function

    CST2 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CST2 itself. We selected most functions CST2 had, and list some proteins which have the same functions with CST2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding IRAK4,ECSIT,CENPJ,TCF7,CYGB,DCUN1D1,BAZ1A,SHARPIN,NECAB3,DBC1
    cysteine-type endopeptidase inhibitor activity BIRC7,CST3,SPOCK1,NLRC4,BIRC5B,FETUB,SERPINB3,SERPINB13,BIRC5A,CARD18

    Interacting Protein

    CST2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CST2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CST2.

    PSMA3;ADAMTSL4;NOTCH2NL

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