cst2
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  • Official Full Name
  • cystatin SA
  • Background
  • The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma.
  • Synonyms
  • CST2; cystatin SA; cystatin-SA; cystatin 2; cystatin-2; cystatin S5; cystatin-S5; cysteine-proteinase inhibitor; salivary cysteine (thiol) protease inhibitor; MGC71924
Cat.#:CST2-2024HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CST2 Protein, GST-tagged
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Cat.#:CST2-3357HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CST2 Protein, MYC/DDK-tagged
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Cat.#:CST2-1662HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CST2 protein, His-tagged
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Cat.#:CST2-195HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human CST2 Protein, His-tagged
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Cat.#:CST2-3214HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CST2, His tagged
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Cat.#:CST2-2240HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CST2 cell lysate
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Involved Pathway

CST2 involved in several pathways and played different roles in them. We selected most pathways CST2 participated on our site, such as Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CST2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Salivary secretion
CALM1; PRB1; MUC5B; CD38; PRKCB; CAMP; NOS1; GUCY1B3; BST1; GUCY1A3

Protein Function

CST2 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CST2 itself. We selected most functions CST2 had, and list some proteins which have the same functions with CST2. You can find most of the proteins on our site.
Function
Related Protein
Function cysteine-type endopeptidase inhibitor activity
Related Protein CST6; Cstb; CST2; KNG1; CARD18; AHSG; CARD17; AHSG1; CST9L; STFA2
Function protein binding
Related Protein SCNN1G; CKS1B; KCNJ3; CASP10; MRPL9; OTOF; MRPL11; ACVR1L; SNX31; CERS2

Interacting Protein

CST2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CST2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CST2.
PSMA3; ADAMTSL4; NOTCH2NL