CYP2U1
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Official Full Name
cytochrome P450, family 2, subfamily U, polypeptide 1
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Overview
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. -
Synonyms
CYP2U1; cytochrome P450, family 2, subfamily U, polypeptide 1; cytochrome P450 2U1; CP2U1_HUMAN; CYP2U 1; EC 1.14.14.1; P450TEC;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CYP2U1-2270H | Recombinant Human CYP2U1 Protein, GST-tagged | Wheat Germ | GST |
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| Human | CYP2U1-435HCL | Recombinant Human CYP2U1 cell lysate | N/A |
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| Human | CYP2U1-2395HF | Recombinant Full Length Human CYP2U1 Protein, GST-tagged | In Vitro Cell Free System | GST | 168 amino acids |
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| Human | CYP2U1-3939H | Recombinant Human CYP2U1 protein, His-tagged | E.coli | His | 1-59 aa | |
| Mouse | CYP2U1-4203M | Recombinant Mouse CYP2U1 Protein | Mammalian Cell | His |
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| Mouse | CYP2U1-2151M | Recombinant Mouse CYP2U1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | CYP2U1-2151M-B | Recombinant Mouse CYP2U1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | CYP2U1-1742R | Recombinant Rat CYP2U1 Protein | Mammalian Cell | His |
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| Rat | CYP2U1-1401R-B | Recombinant Rat CYP2U1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | CYP2U1-1401R | Recombinant Rat CYP2U1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Bos taurus (Bovine) | RFL439BF | Recombinant Full Length Bovine Cytochrome P450 2U1(Cyp2U1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-543) |
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| Homo sapiens (Human) | RFL15545HF | Recombinant Full Length Human Cytochrome P450 2U1(Cyp2U1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-544) |
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| Mus musculus (Mouse) | RFL29322MF | Recombinant Full Length Mouse Cytochrome P450 2U1(Cyp2U1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-530) |
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| Rattus norvegicus (Rat) | RFL26258RF | Recombinant Full Length Rat Cytochrome P450 2U1(Cyp2U1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-530) |
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| Zebrafish | CYP2U1-7322Z | Recombinant Zebrafish CYP2U1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- CYP2U1 Related Articles
CYP2U1 involved in several pathways and played different roles in them. We selected most pathways CYP2U1 participated on our site, such as Arachidonic acid metabolism, Biological oxidations, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP2U1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arachidonic acid metabolism | PLA2G1B;CBR3;CYP2AD3;FAAH2;CYP2P9;CBR2;CYP4F22;CYP4F3;CYP2B6 |
| Biological oxidations | SLC35B2;CYP2AD6;PRKRA;CYP17A1;CYP2K18;CYP2U1;CYP2K19;ABHD10;ACY3 |
| Cytochrome P450 - arranged by substrate type | CYP1B1;CYP2N13;CYP2K18;CYP11B2;CYP4F11;CYP2K19;CYP2D6;CYP4F22;CYP2V1 |
| Metabolic pathways | PRODH2;IMPDH1B;GLUD1;TKTL2;EHHADH;ACADSB;ATP6V1E2;MINPP1;PTGES2 |
| Metabolism | GYG1A;NDUFAF7;FAM96B;SREBF2;NDUFAF5;TACO1;MED16;SURF1;CYB5R3 |
| Metabolism of lipids and lipoproteins | MED22;CDIPT;SACM1LA;COL4A3BP;MED31;PIK3R6;PLBD1;CYP27A1;CPNE6 |
| Miscellaneous substrates | CYP2S1;CYP2K8;CYP4B1;CYP2K19;CYP2K6;CYP2U1;CYP2K18;CYP2K16;CYP3C1 |
| Phase 1 - Functionalization of compounds | CYP4F12;CYP2N13;CYP2F1;CYP2K22;CYP2AD2;CYP3C1;ADH8A;CYP2W1;CYP2V1 |
CYP2U1 has several biochemical functions, for example, aromatase activity, heme binding, iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP2U1 itself. We selected most functions CYP2U1 had, and list some proteins which have the same functions with CYP2U1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aromatase activity | CYP2A7;CYP2J2;CYP2S1;FAM84B;CYP2J6;CYP2F1;CYP2C9;CYP1A;CYP2D9 |
| heme binding | CYP2X10.2;CYP11B2;CYP17A2;CYP51;MPO;HMOX1;FA2H;PTGESL;CYP21A2 |
| iron ion binding | CYP8B2;CYP1A4;CYP17A1;TYW1;FAXDC2;HBAE1;CYP2F1;ACO2;PAH |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | CYP2AD3;CYP2K16;CYP2C70;CYP2X8;CYP2A13;CYP2K17;CYP2AA3;CYP2A6;CYP2B19 |
| oxygen binding | HBAA;XGB;HBBE2;CYP2C54;CYP2AA7;CYP2F2;CYP2N13;CYP1A4;HBAE3 |
| steroid hydroxylase activity | CYP2A12;CYP2P7;BRSK2;CYP2K22;CH25H;CYP2C9;CYP2X7;CYP2X8;CYP2C8 |
CYP2U1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP2U1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP2U1.
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