Cyp11b2 Protein, cytochrome P450, family 11, subfamily b, polypeptide 2


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Official Full Name cytochrome P450, family 11, subfamily b, polypeptide 2
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Yeast
    • Tag :
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CYP11B2-2190H Recombinant Human CYP11B2 Protein (25-503 aa), His-tagged Yeast His
    Human CYP11B2-1179H Recombinant Human CYP11B2 Protein, His/SUMO-tagged E.coli His/SUMO
    Human CYP11B2-194H Recombinant Human CYP11B2 Mammalian Cell His
    Human CYP11B2-7129HCL Recombinant Human CYP11B2 293 Cell Lysate HEK293 N/A
    Rhesus Macaque CYP11B2-1134R Recombinant Rhesus monkey CYP11B2 Protein, His-tagged Mammalian Cell His

    Cyp11b2 involved in several pathways and played different roles in them. We selected most pathways Cyp11b2 participated on our site, such as ACE Inhibitor Pathway, Aldosterone synthesis and secretion, Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cyp11b2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ACE Inhibitor Pathway ATP6AP2; AGT; CYP11B2; AGTR1; CTSG; AGTR2; ACE; CMA1
    Aldosterone synthesis and secretion PRKACB; Adcy4; CAMK4; PRKD2; ADCY9; MC2R; KCNK3; AGTR1B; CACNA1G; CALM4
    Biological oxidations ADH7; ADH8B; ADH1B; ADH8A; CYP2A13; CYP2AD2; CYP2Y3; UGT1B4; CYP26A1; ADH4
    Cytochrome P450 - arranged by substrate type CYP7A1; FDXR; CYP2K22; CYP19A1; CYP2Y3; CYP27B1; CYP2A7; CYP8B2; CYP4F11; CYP2AD3
    Endogenous sterols FDX1; CYP11A1; FDX1L; CYP51A1; CYP8B2; CYP1B1; CYP17A1; CYP27A1; CYP46A1; FDXR
    Glucocorticoid &amp CYP21A2; CYP17A1; AKR1C21; CYP11B2
    amp CYP17A1; CYP21A2; CYP11B2; AKR1C21
    Mineralcorticoid Metabolism CYP11B2; CYP21A2; CYP17A1; AKR1C21
    Glucocorticoid biosynthesis CYP21A2; CYP17A1; CYP11B2; CYP11B1
    Metabolic pathways ATP6V1H; CTPS1A; INPP5L; ALG3; TK1; R05D11.9; GCDH; GANC; PIGK; DEGS1

    Cyp11b2 has several biochemical functions, for example, corticosterone 18-monooxygenase activity, heme binding, iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Cyp11b2 itself. We selected most functions Cyp11b2 had, and list some proteins which have the same functions with Cyp11b2. You can find most of the proteins on our site.

    Function Related Protein
    corticosterone 18-monooxygenase activity CYP11C1; CYP11B1; CYP11B2
    heme binding CYP20A1; HBBE1.1; CYP4F11; HBB-BH1; CYP27A1; CYP2C9; CYP2D6; CYP2F1; CYP1C2; CYP46A1.1
    iron ion binding CYP2F2; ALOX5A; CYP19A1; XDH; TYW1; CYP2K16; NDOR1; CYP3C1; HBD; ALKBH8
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen CYP4F18; MTRR; CYP11B2; POR; CYP4F11; MICAL2; CYP11B1; CYP2E1; CYP4F2; NDOR1
    steroid 11-beta-monooxygenase activity CYP11C1; CYP11B1; CYP11B2

    Cyp11b2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cyp11b2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cyp11b2.

    Kuppusamy, M; Caroccia, B; et al. A Novel KCNJ5-insT149 Somatic Mutation Close to, but Outside, the Selectivity Filter Causes Resistant Hypertension by Loss of Selectivity for Potassium. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 99:E1765-E1773(2014).
    Nakamura, Y; Maekawa, T; et al. Adrenal CYP11B1/2 expression in primary aldosteronism: Immunohistochemical analysis using novel monoclonal antibodies. MOLECULAR AND CELLULAR ENDOCRINOLOGY 392:73-79(2014).

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